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Bautista Aguilera, Óscar Mauricio

Química Orgánica y Química Inorgánica / Universidad de Alcalá

Publications

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1−42Aggregation Inhibitors for Alzheimer's Disease Therapy

  • Dgachi, Y.
  • Ismaili, L.
  • Knez, D.
  • Benchekroun, M.
  • Martin, H.
  • Szałaj, N.
  • Wehle, S.
  • Bautista-Aguilera, O.M.
  • Luzet, V.
  • Bonnet, A.
  • Malawska, B.
  • Gobec, S.
  • Chioua, M.
  • Decker, M.
  • Chabchoub, F.
  • Marco-Contelles, J.
... View more Collapse

ChemMedChem (p. 1318-1327) - 2016

Editor: John Wiley and Sons Ltd

10.1002/cmdc.201500539 View at source

  • ISSN/ISBN 1860-7187

Design, Synthesis and Biological Evaluation of Potent Antioxidant 1-(2,5-Dimethoxybenzyl)-4-arylpiperazines and N-Azolyl Substituted 2-(4-Arylpiperazin-1-yl)

  • Saadeh, H.A.
  • Khasawneh, M.A.
  • Samadi, A.
  • El-Haty, I.A.
  • Satała, G.
  • Bojarski, A.J.
  • Ismaili, L.
  • Bautista-Aguilera, Ó.M.
  • Yañez, M.
  • Mestres, J.
  • Marco-Contelles, J.
... View more Collapse

ChemistrySelect (p. 3854-3859) - 2017

Editor: Wiley-Blackwell

10.1002/slct.201700397 View at source

  • ISSN/ISBN 2365-6549

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

  • Bautista-Aguilera, Ó.M.
  • Hagenow, S.
  • Palomino-Antolin, A.
  • Farré-Alins, V.
  • Ismaili, L.
  • Joffrin, P.-L.
  • Jimeno, M.L.
  • Soukup, O.
  • Janočková, J.
  • Kalinowsky, L.
  • Proschak, E.
  • Iriepa, I.
  • Moraleda, I.
  • Schwed, J.S.
  • Romero Martínez, A.
  • López-Muñoz, F.
  • Chioua, M.
  • Egea, J.
  • Ramsay, R.R.
  • Marco-Contelles, J.
  • Stark, H.
... View more Collapse

Angewandte Chemie - International Edition (p. 12765-12769) - 2017

Editor: Wiley-VCH Verlag

10.1002/anie.201706072 View at source

  • ISSN/ISBN 1521-3773

Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile

  • Bautista-Aguilera, O.M.
  • Budni, J.
  • Mina, F.
  • Medeiros, E.B.
  • Deuther-Conrad, W.
  • Entrena, J.M.
  • Moraleda, I.
  • Iriepa, I.
  • López-Muñoz, F.
  • Marco-Contelles, J.
... View more Collapse

Journal of Medicinal Chemistry (p. 6937-6943) - 2018

Editor: American Chemical Society

10.1021/acs.jmedchem.8b00848 View at source

  • ISSN/ISBN 1520-4804

Label-Free Whole Cell Biosensing for High-Throughput Discovery of Activators and Inhibitors Targeting G Protein-Activated Inwardly Rectifying Potassium Channels

  • Krebs, K.M.
  • Pfeil, E.M.
  • Simon, K.
  • Grundmann, M.
  • Häberlein, F.
  • Bautista-Aguilera, O.M.
  • Gütschow, M.
  • Weaver, C.D.
  • Fleischmann, B.K.
  • Kostenis, E.
... View more Collapse

ACS Omega (p. 14814-14823) - 2018

Editor: American Chemical Society

10.1021/acsomega.8b02254 View at source

  • ISSN/ISBN 2470-1343

In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases

  • Wiȩckowska, A.
  • Szałaj, N.
  • Góral, I.
  • Bucki, A.
  • Latacz, G.
  • Kiec-Kononowicz, K.
  • Bautista-Aguilera, Ò.M.
  • Romero, A.
  • Ramos, E.
  • Egea, J.
  • Farré Alíns, V.
  • González-Rodríguez, Á.
  • López-Muñoz, F.
  • Chioua, M.
  • Marco-Contelles, J.
... View more Collapse

ACS Chemical Neuroscience (p. 3793-3801) - 2020

Editor: American Chemical Society

10.1021/acschemneuro.0c00489 View at source

  • ISSN/ISBN 1948-7193

Automated Synthesis of New Quinoxalinetacrines

  • Bautista-Aguilera, Ó.M.
  • Ismaili, L.
  • Chioua, M.
  • Iriepa, I.
  • Ángeles Martinez-Grau, M.
  • Beadle, C.D.
  • Vetman, T.
  • López-Muñoz, F.
  • Marco-Contelles, J.
... View more Collapse

ChemistrySelect (p. 6491-6493) - 2020

Editor: Wiley-Blackwell

10.1002/slct.202001593 View at source

  • ISSN/ISBN 2365-6549

Acetylcholinesterase inhibition of diversely functionalized quinolinones for alzheimer’s disease therapy

  • Bautista-Aguilera, Ó.M.
  • Ismaili, L.
  • Chioua, M.
  • Andrys, R.
  • Schmidt, M.
  • Bzonek, P.
  • Martínez-Grau, M.Á.
  • Beadle, C.D.
  • Vetman, T.
  • López-Muñoz, F.
  • Iriepa, I.
  • Refouvelet, B.
  • Musilek, K.
  • Marco-Contelles, J.
... View more Collapse

International Journal of Molecular Sciences (p. 1-20) - 2020

Editor: MDPI AG

10.3390/ijms21113913 View at source

  • ISSN/ISBN 1422-0067

Triazolopyridopyrimidine: A new scaffold for dual-target small molecules for Alzheimer's disease therapy

  • Zribi, L.
  • Pachòn-Angona, I.
  • Bautista-Aguilera, O.M.
  • Diez-Iriepa, D.
  • Marco-Contelles, J.
  • Ismaili, L.
  • Iriepa, I.
  • Chabchoub, F.
... View more Collapse

Molecules - 2020

Editor: MDPI AG

10.3390/molecules25143190 View at source

  • ISSN/ISBN 1420-3049

Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments

  • Bautista-Aguilera, Ó.M.
  • Ismaili, L.
  • Iriepa, I.
  • Diez-Iriepa, D.
  • Chabchoub, F.
  • Marco-Contelles, J.
  • Pérez, M.
... View more Collapse

Chemical Record (p. 162-174) - 2021

Editor: John Wiley and Sons Inc

10.1002/tcr.202000107 View at source

  • ISSN/ISBN 1528-0691

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Last data update: 4/24/24 1:00 PM