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Ríos Salgado, Cristóbal de los cristobal.delosrios@urjc.es

Ciencias Básicas de la Salud / Universidad Rey Juan Carlos

Actividades

1,8-Naphthyridine Derivatives as Cholinesterases Inhibitors and Cell Ca2+ Regulators, a Multitarget Strategy for Alzheimer's Disease

  • Egea, Javier
  • de los Rios, Cristobal;

Current Topics In Medicinal Chemistry (p. 2807-2823) - 1/11/2011

10.2174/156802611798184418 Ver en origen

  • ISSN 15680266

Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles

  • Villarroya Sanchez, Mercedes
  • Garcia Lopez, Manuela
  • Gandia Juan, Luis
  • Samadi, Abdelouahid
  • Valderas, Carolina
  • de los Rios, Cristobal
  • Bastida, Agatha
  • Chioua, Mourad
  • Gonzalez-Lafuente, Laura
  • Colmena, Ines
  • Gandia, Luis
  • Romero, Alejandro
  • del Barrio, Laura
  • Martin-De-Saavedra, Maria D
  • Lopez, Manuela G
  • Villarroya, Mercedes
  • Marco-Contelles, Jose
... Ver más Contraer

Bioorganic & Medicinal Chemistry (p. 122-133) - 1/1/2011

10.1016/j.bmc.2010.11.040 Ver en origen

  • ISSN 14643391

Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists

  • Tomassoli I, Ismaili L, Pudlo M, de Los Ríos C, Soriano E, Colmena I, Gandía L, Rivas L, Samadi A, Marco-Contelles J, Refouvelet B

European Journal Of Medicinal Chemistry (p. 1-10) - 1/1/2011

10.1016/j.ejmech.2010.08.054 Ver en origen

  • ISSN 02235234

Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles

  • Villarroya Sanchez, Mercedes
  • Garcia Lopez, Manuela
  • Garcia Garcia, Antonio
  • Gandia Juan, Luis
  • Samadi, Abdelouahid
  • Marco-Contelles, Jose
  • Soriano, Elena
  • Alvarez-Perez, Monica
  • Chioua, Mourad
  • Romero, Alejandro
  • Gonzalez-Lafuente, Laura
  • Gandia, Luis
  • Roda, Jose M
  • Lopez, Manuela G
  • Villarroya, Mercedes
  • Garcia, Antonio G
  • Rios, Cristobal de Los
... Ver más Contraer

Bioorganic & Medicinal Chemistry (p. 5861-5872) - 15/8/2010

10.1016/j.bmc.2010.06.095 Ver en origen

  • ISSN 14643391

Synthesis, Inhibitory Activity of Cholinesterases, and Neuroprotective Profile of Novel 1,8-Naphthyridine Derivatives

  • De Los Ríos, C.
  • Egea, J.
  • Marco-Contelles, J.
  • León, R.
  • Samadi, A.
  • Iriepa, I.
  • Moraleda, I.
  • Gálvez, E.
  • García, A.G.
  • López, M.G.
  • Villarroya, M.
  • Romero, A.
... Ver más Contraer

Journal Of Medicinal Chemistry (p. 5129-5143) - 22/7/2010

10.1021/jm901902w Ver en origen

  • ISSN 00222623
  • ISSN/ISBN 0022-2623

Molecular modelling, synthesis and acetylcholinesterase inhibition of ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][1,8]naphthyridine-3-carboxylate

  • Soriano, Elena
  • Samadi, Abdelouahid
  • Chioua, Mourad
  • de los Rios, Cristobal
  • Marco-Contelles, Jose;

Bioorganic & Medicinal Chemistry Letters (p. 2950-2953) - 1/5/2010

10.1016/j.bmcl.2010.03.010 Ver en origen

  • ISSN 0960894X

Tacripyrines, the First Tacrine-Dihydropyridine Hybrids, as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease

  • Villarroya Sanchez, Mercedes
  • Garcia Lopez, Manuela
  • Garcia Garcia, Antonio
  • Marco-Contelles, Jose
  • Leon, Rafael
  • de los Rios, Cristobal
  • Samadi, Abdelouahid
  • Bartolini, Manuela
  • Andrisano, Vincenza
  • Huertas, Oscar
  • Barril, Xavier
  • Luque, F Javier
  • Rodriguez-Franco, Maria I
  • Lopez, Beatriz
  • Lopez, Manuela G
  • Garcia, Antonio G
  • Carreiras, Maria Do Carmo
  • Villarroya, Mercedes
... Ver más Contraer

Journal Of Medicinal Chemistry (p. 2724-2732) - 14/5/2009

10.1021/jm801292b Ver en origen

  • ISSN 00222623

Anthracene Based Compounds as New L-type Ca2+ Channel Blockers: Design, Synthesis, and Full Biological Profile

  • Bova, Sergio
  • Saponara, Simona
  • Rampa, Angela
  • Gobbi, Silvia
  • Cima, Lorenzo
  • Fusi, Fabio
  • Sgaragli, Giampietro
  • Cavalli, Maurizio
  • de los Rios, Cristobal
  • Striessnig, Joerg
  • Bisi, Alessandra;
... Ver más Contraer

Journal Of Medicinal Chemistry (p. 1259-1262) - 12/3/2009

10.1021/jm801589x Ver en origen

  • ISSN 00222623

New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties

  • Villarroya Sanchez, Mercedes
  • Garcia Lopez, Manuela
  • Garcia Garcia, Antonio
  • Leon, Rafael
  • de los Rios, Cristobal
  • Marco-Contelles, Jose
  • Huertas, Oscar
  • Barril, Xavier
  • Luque, F Javier
  • Lopez, Manuela G
  • Garcia, Antonio G
  • Villarroya, Mercedes
... Ver más Contraer

Bioorganic & Medicinal Chemistry (p. 7759-7769) - 15/8/2008

10.1016/j.bmc.2008.07.005 Ver en origen

  • ISSN 14643391

Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death

  • Villarroya Sanchez, Mercedes
  • Garcia Lopez, Manuela
  • Garcia Garcia, Antonio
  • Leon, Rafael
  • de los Rios, Cristobal
  • Marco-Contelles, Jose
  • Lopez, Manuela G
  • Garcia, Antonio G
  • Villarroya, Mercedes
... Ver más Contraer

European Journal Of Medicinal Chemistry (p. 668-674) - 1/3/2008

10.1016/j.ejmech.2007.06.001 Ver en origen

  • ISSN 02235234

Este/a investigador/a no tiene libros.

Este/a investigador/a no tiene capítulos de libro.

Mitochondrial Na+/Ca2+ exchanger (NCLX) participates in NLRP3 inflammasome activation

  • Narros Fernandez, Paloma
  • Palomino Antolin, Alejandra
  • Farre Alins, Victor
  • De los Rios, Cristobal
  • Egea, Javier;

Basic & Clinical Pharmacology & Toxicology (p. 51-52) - 1/11/2019

  • ISSN 17427835
  • iMarina

ROLE OF THE MITOCHONDRIAL NA+/CA2+EXCHANGER IN NLRP3 INFLAMMASOME ACTIVATION

  • Fernandez, P. N.
  • Antolin, A. P.
  • Alins, V. F.
  • Rosa, J. M.
  • de los Rios, C.
  • Egea, J.;

Basic & Clinical Pharmacology & Toxicology (p. 38-38) - 1/8/2018

  • ISSN 17427835
  • iMarina

NEW DUAL NEUROPROTECTANTS BASED ON 3-SUBSTITUTED INDOLE DERIVATIVES TARGETING BOTH CALCIUM CHANNELS AND PHOSPHOPROTEIN PHOSPHATASE 2A

  • Gandia Juan, Luis

Basic & Clinical Pharmacology & Toxicology (p. 40-41) - 1/9/2014

  • ISSN 17427835
  • iMarina

Syntheses and reactions of optically active alpha-aminoallenyistannanes and alpha-aminopropargylboranes

  • Hegedus, LS
  • Ranslow, P
  • Achmatowicz, M
  • de los Rios, C
  • Hyland, C
  • Garcia-Frutos, EM
  • Salman, S;
... Ver más Contraer

Pure And Applied Chemistry (p. 333-339) - 1/2/2006

10.1351/pac200678020333 Ver en origen

  • ISSN 00334545

ITH4012, a novel acetylcholinesterase inhibitor with 'calcium promoter' and neuroprotective properties

  • Villarroya, M
  • Orozco, C
  • de los Rios, C
  • Arias, E
  • Leon, R
  • Garcia, AG
  • Marco, JL
  • Lopez, MG
... Ver más Contraer

Journal Of Neurochemistry (p. 240-240) - 1/8/2005

  • ISSN 00223042
  • iMarina

Este/a investigador/a no tiene documentos de trabajo.

Este/a investigador/a no tiene informes técnicos.

Este/a investigador/a no tiene proyectos de investigación.

Este/a investigador/a no tiene tesis dirigidas.

Este/a investigador/a no tiene patentes o licencias de software.

Última actualización de los datos: 24/04/24 13:11