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Author profile at the institutional portal

Hernandez Perez, Felix felix.hernandez@uam.es

Biología molecular / Universidad Autónoma de Madrid

Publications

Different modes of synaptic and extrasynaptic NMDA receptor alteration in the hippocampus of P301S tau transgenic mice

  • Alfaro-Ruiz R
  • Aguado C
  • Martín-Belmonte A
  • Moreno-Martínez AE
  • Merchán-Rubira J
  • Hernández F
  • Ávila J
  • Fukazawa Y
  • Luján R
... View more Collapse

Brain Pathology - 1/1/2023

10.1111/bpa.13115 View at source

  • ISSN 10156305

Microtubule-associated protein tau in murine kidney: role in podocyte architecture

  • Vallés-Saiz L, Peinado-Cahuchola R, Ávila J, Hernández F

Cellular And Molecular Life Sciences - 1/2/2022

10.1007/s00018-021-04106-z

  • ISSN 1420682X
  • iMarina

Alteration in the Synaptic and Extrasynaptic Organization of AMPA Receptors in the Hippocampus of P301S Tau Transgenic Mice

  • Alfaro-Ruiz, R.
  • Aguado, C.
  • Martín-Belmonte, A.
  • Moreno-Martínez, A.E.
  • Merchán-Rubira, J.
  • Hernández, F.
  • Ávila, Jesus
  • Fukazawa, Y.
  • Luján, R.
... View more Collapse

International Journal Of Molecular Sciences - 22/12/2022

10.3390/ijms232113527 View at source

  • ISSN 14220067

p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model

  • Perea, J.R.
  • García, E.
  • Vallés-Saiz, L.
  • Cuadros, R.
  • Hernández, F.
  • Bolós, M.
  • Avila, J.
... View more Collapse

Scientific Reports - 1/12/2022

10.1038/s41598-022-05980-8 View at source

  • ISSN 20452322

Neuronal nuclear tau and neurodegeneration

  • Antón-Fernández, A.
  • Vallés-Saiz, L.
  • Avila, J.
  • Hernández, F.

Neuroscience (p. 178-184) - 1/1/2022

10.1016/j.neuroscience.2022.07.015 View at source

  • ISSN 03064522

Mouse and Human Tau Expression in Different Brain Areas

  • Valles-Saiz, L.
  • Ruiz-Gabarre, D.
  • Garcia-Escudero, V.
  • Perry, G.
  • Avila, J.
  • Hernandez, F.

J Alzheimers Dis Rep (p. 677-684) - 1/1/2022

10.3233/adr-220051 View at source

  • ISSN 25424823

CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington’s disease

  • Picó S
  • Parras A
  • Santos-Galindo M
  • Pose-Utrilla J
  • Castro M
  • Fraga E
  • Hernández IH
  • Elorza A
  • Anta H
  • Wang N
  • Martí-Sánchez L
  • Belloc E
  • Garcia-Esparcia P
  • Garrido JJ
  • Ferrer I
  • Macías-García D
  • Mir P
  • Artuch R
  • Pérez B
  • Hernández F
  • Navarro P
  • López-Sendón JL
  • Iglesias T
  • William Yang X
  • Méndez R
  • Lucas JJ
... View more Collapse

Science Translational Medicine - 29/9/2021

10.1126/scitranslmed.abe7104 View at source

  • ISSN 19466234

A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease

  • García-Escudero V
  • Ruiz-Gabarre D
  • Gargini R
  • Pérez M
  • García E
  • Cuadros R
  • Hernández IH
  • Cabrera JR
  • García-Escudero R
  • Lucas JJ
  • Hernández F
  • Ávila J
... View more Collapse

Acta Neuropathologica (p. 159-177) - 1/7/2021

10.1007/s00401-021-02317-z View at source

  • ISSN 00016322

Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration

  • Galán-Ganga M
  • Rodríguez-Cueto C
  • Merchán-Rubira J
  • Hernández F
  • Ávila J
  • Posada-Ayala M
  • Lanciego JL
  • Luengo E
  • Lopez MG
  • Rábano A
  • Fernández-Ruiz J
  • Lastres-Becker I
... View more Collapse

Acta Neuropathologica Communications - 1/12/2021

10.1186/s40478-021-01196-5 View at source

  • ISSN 20515960

The Expression and Localisation of G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels Is Differentially Altered in the Hippocampus of Two Mouse Models of Alzheimer's Disease

  • Alfaro-Ruiz, R
  • Martin-Belmonte, A
  • Aguado, C
  • Hernandez, F
  • Moreno-Martinez, AE
  • Avila, J
  • Lujan, R
... View more Collapse

International Journal Of Molecular Sciences - 1/10/2021

10.3390/ijms222011106 View at source

  • ISSN 14220067

Transgenic mice overexpressing GSK-3 beta as animal models for Alzheimer's disease

  • Hernández, F.

Rsc Drug Discovery Series (p. 52-68) - 1/1/2011

  • ISBN 978-1-84973-275-8
  • ISSN 20413203
  • iMarina

Tau Phosphorylation

  • Avila, Jesus
  • Hernandez, Felix;

Advances In Neurobiology (p. 73-82) - 1/1/2011

10.1007/978-1-4419-6787-9_3 View at source

  • ISSN 21905215

Measurement of cyclic GMP formation

  • Hernández F

Signal Transduction Protocols (p. 107-112) - 1/1/1995

10.1385/0-89603-298-1:107 View at source

  • ISSN 10643745

Huntington's disease as a tauopathy

  • Fernandez-Nogales, M.
  • Cabrera, J. R.
  • Santos-Galindo, M.
  • Hoozemans, J. J. M.
  • Ferrer, I.
  • Rozemuller, A. J. M.
  • Hernandez, F.
  • Avila, J.
  • Lucas, J. J.;
... View more Collapse

Journal Of Neurology Neurosurgery And Psychiatry (p. A17-A17) - 1/9/2014

10.1136/jnnp-2014-309032.52 View at source

  • ISSN 00223050

Co-expression of FTDP-17 human tau and GSK-3 beta (or APP(SW)) in transgenic mice: Induction of tau polymerization and neurodegeneration

  • Avila, Jesus
  • Engel, Tobias
  • Lucas, Jose J.
  • Perez, Mar
  • Rubio, Alicia
  • Hernandez, Felix;

Advances In Alzheimer's And Parkinson's Disease: Insights, Progress, And Perspectives (p. 337-342) - 1/1/2008

10.1007/978-0-387-72076-0_35 View at source

  • ISSN 00999962

Coexpression of FTDP-17 human tau and GSK-3 beta in transgenic mice synergistically act to induce tau polymerization and neurodegeneration

  • Avila, J
  • Engel, I
  • Lucas, JJ
  • Gomez-Ramos, P
  • Moran, MA
  • Hernandez, F

European Neuropsychopharmacology - 1/10/2005

  • ISSN 0924977X
  • iMarina

Different ways for tau assembly

  • Avila, J
  • Perez, M
  • Gomez, A
  • Santa-Maria, I
  • Moreno, F
  • Hernandez, F;

Neurobiology Of Aging (p. S41-S41) - 1/7/2004

10.1016/s0197-4580(04)80135-0 View at source

  • ISSN 01974580

Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain

  • Díaz-Hernández M
  • Moreno-Herrero F
  • Gómez-Ramos P
  • Morán MA
  • Ferrer I
  • Baró AM
  • Avila J
  • Hernández F
  • Lucas JJ
... View more Collapse

Journal Of Neuroscience (p. 9361-9371) - 20/10/2004

10.1523/jneurosci.2365-04.2004 View at source

  • ISSN 15292401

Tau phosphorylation by GSK3

  • Avila, J
  • Hernandez, F
  • Gomez, A
  • Perez, M
  • Lim, F
  • Lucas, JJ

Neurobiology Of Aging (p. S8-S9) - 1/7/2002

  • ISSN 01974580
  • iMarina

Phosphorylation, microtubule binding and aggregation of tau protein in Alzheimer's disease

  • Perez Martinez, Maria Mar

Alzheimer´s Disease: Advances In Etiology, Pathogenesis And Therapeutics (p. 601-607) - 1/1/2001

10.1002/0470846453.ch55 View at source

Differentiation of KCl-, NMDA- and glutamate-evoked cGMP accumulations in the guinea-pig cerebellum

  • Neil, KE
  • Hernandez, F
  • Kendall, DA
  • Alexander, SPH

British Journal Of Pharmacology - 1/10/1997

  • ISSN 00071188
  • iMarina

The effects of the isoenzyme-selective phosphodiesterase inhibitors, rolipram and zaprinast, on cyclic nucleotide levels in the guinea-pig cerebellum

  • Neil, KE
  • Hernandez, F
  • Kendall, DA
  • Alexander, SPH;

British Journal Of Pharmacology (p. P289-P289) - 1/4/1996

  • ISSN 00071188
  • iMarina

The effects of isoprenaline on cyclic-nucleotide levels in the guinea-pig brain

  • WALLACE, KE
  • HERNANDEZ, F
  • KENDALL, DA
  • ALEXANDER, SPH;

British Journal Of Pharmacology (p. P137-P137) - 1/10/1995

  • ISSN 00071188
  • iMarina

This researcher has no working papers.

This researcher has no technical reports.

Neurorregeneración en la enfermedad de Alzheimer a través de la expresión de factores de pluripotencia in vivo

  • García García, Esther (Investigador/a)
  • CUADROS CATALAN, RAQUEL (Investigador/a)
  • Hernandez Perez, Felix (Investigador principal (IP))

Period: 01-09-2021 - 31-08-2024

Type of funding: National

Amount of funding: 181500,00 Euros.

  • iMarina

Bases metabólicas de la neurodegeneración (NEUROMETA-CM)

  • SANCHEZ LANZAS, RAUL (Miembro del equipo de investigación)
  • Gonzalez Castaño, Jose (Investigador principal (IP))
  • Hernandez Perez, Felix (Investigador principal (IP))
  • Diaz Nido, Javier (Investigador principal (IP))

Period: 01-01-2018 - 31-12-2021

  • iMarina

Nuevas aproximaciones al estudio del metabolismo de la GSK3B y de su principal sustrato en el sistema nervioso central, la proteína TAU: implicaciones en la neurogénesis adulta

  • Hernandez Perez, Felix (Investigador/a)

Period: 30-12-2016 - 29-12-2019

Type of funding: National

Amount of funding: 133100,00 Euros.

  • iMarina

Análisis de la función de GSK-3BETA en la neurogénesis adulta en ratones transgénicos con expresión condicional de la quinasa

  • Almudena Fuster Matanzo (Investigador/a)
  • Hernandez Perez, Felix (Investigador principal (IP))

Period: 01-01-2014 - 31-12-2016

  • iMarina

Redes de señalización y vías efectoras en modelos celulares y animales de enfermedades neurodegenerativas. NEURODEGMODELS4 NEUROUAM3

  • Gonzalez Castaño, Jose (Investigador principal (IP))
  • Hernandez Perez, Felix (Investigador principal (IP))
  • Diaz Nido, Javier (Investigador principal (IP))

Period: 01-01-2012 - 31-12-2015

Amount of funding: 106472,00 Euros.

  • iMarina

Activación de la ruta calpaina/GSK-3/CDK-5 en la enfermedad de Alzheimer.

  • Hernandez Perez, Felix (Investigador principal (IP))

Period: 11-01-2009 - 31-10-2012

  • iMarina

Uso de la mucosa olfativa para estudiar patología y mecanismos de regeneración en el sistema nervioso.

  • Benitez Moreno, Maria Jose (Investigador/a)
  • Hernandez Perez, Felix (Investigador/a)
  • Lim, Filip (Investigador principal (IP))

Period: 01-01-2009 - 31-12-2009

  • iMarina

Mecanismos moleculares de la neurodegeneración Modelos celulares y animales.

  • Palomo Carrasco, Gloria María (Investigador/a)
  • Alfredo Gimenez Casina Sendon (Investigador/a)
  • Erika Pastrana Izquierdo (Investigador/a)
  • Elena Langa Gabriel (Investigador/a)
  • Paloma Goñi Oliver (Investigador/a)
  • Lim, Filip (Investigador/a)
  • Christina Mauritz (Investigador/a)
  • Antonia Cerrato Gomez (Investigador/a)
  • Diaz Nido, Javier (Investigador principal (IP))
  • Hernandez Perez, Felix (Investigador principal (IP))
... View more Collapse

Period: 01-01-2007 - 31-12-2010

  • iMarina

Alteraciones en el sistema ubiquitina-proteosoma en animales transgénicos que sobrexpresan taumut.

  • Tobias Engel (Investigador/a)
  • Elena Langa Gabriel (Investigador/a)
  • Paloma Goñi Oliver (Investigador/a)
  • Hernandez Perez, Felix (Investigador principal (IP))

Period: 01-01-2005 - 31-12-2005

  • iMarina

Nuevas funciones para la proteína tau en el Sistema Nervioso Central y en tejidos periféricos

  • Félix Hernández Pérez (Director) Doctorando: Vallés-Saiz, Laura

1/1/2022

  • iMarina

Efecto de tau en la respuesta inflamatoria de la microglía

  • Perez Martinez, Maria Mar (Autor o Coautor)
  • Ávila de Grado, Jesús (Director)

26/6/2020

  • iMarina

Envejecimiento, Alzheimer y reprogramación celular in vivo.: Efecto de la sobreexpresión de GSK-3B y de los factores de Yamanaka en el sistema nervioso central.

  • Félix Hernández Pérez (Director) Doctorando: García Rodríguez, Alberto

23/6/2020

  • iMarina

Caracterización de un modelo murino de taupatía tau-P301S: Alteraciones en el sistema nervioso periférico y central

  • Bullido Gomez-Heras, Maria Jesus (Autor o Coautor)
  • Félix Hernández Pérez (Director)
  • Jesús Ávila de Grado (Director)
  • Hernandez Perez, Felix (Director)
  • Hernandez Perez, Felix (Autor o Coautor)
  • Ávila de Grado, Jesús (Codirector)

1/1/2020

  • iMarina

Evaluación de compuestos antitumorales dirigidos contra tubulina e implicación en los mecanismos estructurales de control del citoesqueleto

  • Díaz Pereira, J. Fernando (Director)
  • Josa Prado, Fernando (Director)
  • Hernandez Perez, Felix (Tutor) Doctorando: Balaguer Pérez, Francisco de Asís

28/6/2019

  • iMarina

Molecular mechanisms that control synapse number and activity.

  • Alberto Ferrús Gamero (Director)
  • Sergio Casas-Tintó (Director)
  • Hernandez Perez, Felix (Tutor) Doctorando: Elena Santana Martin

11/5/2018

  • iMarina

The effect of age on brain insulin signalling

  • Mayor Menendez, Federico (Autor o Coautor)
  • Adrián Martín (Director)
  • Hernandez Perez, Felix (Autor o Coautor) Doctorando: Adrián Martín

1/1/2017

  • iMarina

Estudio del papel de la proteína TAU en la modulación de la neurogénesis hipocampal adulta

  • Perez Martinez, Maria Mar (Autor o Coautor)
  • Correas Hornero, Maria Isabel (Autor o Coautor)
  • Noemí Pallas?Bazarra (Director)
  • Hernandez Perez, Felix (Autor o Coautor) Doctorando: Noemí Pallas?Bazarra

17/7/2015

  • iMarina

Alteraciones en el transcriptoma y las vías de reparación del dna en modelos celulares neurales de ataxia de friedreich

  • Hernandez Perez, Felix (Autor o Coautor)
  • Jara Moreno Lorite (Director)
  • Diaz Nido, Javier (Autor o Coautor) Doctorando: Jara Moreno Lorite

1/1/2015

  • iMarina

Estudio de la neurogénesis adulta en un modelo murino de sobreexpresión de la glucógeno sintasa quinasa-3 Beta en precursores neuronales

  • Jesús Ávila de Grado (Director)
  • Félix Hernández Pérez (Director) Doctorando: Jerónimo Jurado Arjona

17/1/2014

  • iMarina

A new non- aggregative splicing isoform of human tau is decreased in alzheimers disease

  • García-Escudero Barreras, María Vega (Autor o Coautor)
  • Hernandez Perez, Felix (Autor o Coautor)
  • Ruiz Gabarre, Daniel (Autor o Coautor)

13/10/2022

  • iMarina

Uso de Compuestos Que Se Unen Al Dominio de Union A Microtubulos de Tau en la Elaboracion de Composiciones Farmaceuticas, Dichas Composiciones Farmaceuticas y Su Aplicacion en el Tratamiento de Tautopatias

  • Hernandez Perez, Felix (Autor o Coautor)

26/1/2006

  • iMarina

GSK-3 beta expressed in a transgenic mouse

  • Hernandez Perez, Felix (Inventores/autores/obtentores)

18/9/2003

  • iMarina

New transgenic animal in which glycogen synthase kinase-3 beta protein is over-expressed, useful as model for neurodegenerative disease such as Alzheimer's disease

  • Hernandez Perez, Felix (Autor o Coautor)

18/5/2000

  • iMarina
Last data update: 3/18/24 11:39 PM