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Author profile at the institutional portal

Fernandez Gines, Raquel raquel.fernandezg@uam.es

Medicina / Universidad Autónoma de Madrid

Publications

Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells

  • Patibandla, Chinmai
  • van Aalten, Lidy
  • Dinkova-Kostova, Albena T
  • Honda, Tadashi
  • Cuadrado, Antonio
  • Fernandez-Gines, Raquel
  • Mcneilly, Alison D
  • Hayes, John D
  • Cantley, James
  • Sutherland, Calum
... View more Collapse

Redox Biology - 1/5/2024

10.1016/j.redox.2024.103117

  • ISSN 22132317
  • iMarina

Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH

  • Fernández-Ginés, R
  • Encinar, JA
  • Escoll, M
  • Carnicero-Senabre, D
  • Jiménez-Villegas, J
  • García-Yagüe, AJ
  • González-Rodríguez, A
  • Garcia-Martinez, I
  • Valverde, AM
  • Rojo, AI
  • Cuadrado, A
... View more Collapse

Redox Biology (p. 103027-103027) - 1/2/2024

10.1016/j.redox.2024.103027

  • ISSN 22132317
  • iMarina

Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood

  • Bourdakou MM
  • Fernández-Ginés R
  • Cuadrado A
  • Spyrou GM

Redox Biology - 1/11/2023

10.1016/j.redox.2023.102881 View at source

  • ISSN 22132317

Corrigendum to "An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver" [Redox Biol

  • Fernández-Ginés R, Encinar JA, Hayes JD, Oliva B, Rodríguez-Franco MI, Rojo AI, Cuadrado A

Redox Biology (p. 102428-102428) - 1/9/2022

10.1016/j.redox.2022.102428

  • ISSN 22132317
  • iMarina

The current status and future prospects for therapeutic targeting of KEAP1-NRF2 and β-TrCP-NRF2 interactions in cancer chemoresistance

  • Srivastava R, Fernández-Ginés R, Encinar JA, Cuadrado A, Wells G

Free Radical Biology And Medicine (p. 246-260) - 1/11/2022

10.1016/j.freeradbiomed.2022.09.023

  • ISSN 08915849
  • iMarina

Can Activation of NRF2 Be a Strategy against COVID-19?

  • Cuadrado A
  • Pajares M
  • Benito C
  • Jiménez-Villegas J
  • Escoll M
  • Fernández-Ginés R
  • Garcia Yagüe AJ
  • Lastra D
  • Manda G
  • Rojo AI
  • Dinkova-Kostova AT
... View more Collapse

Trends In Pharmacological Sciences (p. 598-610) - 1/9/2020

10.1016/j.tips.2020.07.003 View at source

  • ISSN 01656147

Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties

  • Herrera-Arozamena C
  • Estrada-Valencia M
  • Pérez C
  • Lagartera L
  • Morales-García JA
  • Pérez-Castillo A
  • Franco-Gonzalez JF
  • Michalska P
  • Duarte P
  • León R
  • López MG
  • Mills A
  • Gago F
  • García-Yagüe ÁJ
  • Fernández-Ginés R
  • Cuadrado A
  • Rodríguez-Franco MI
... View more Collapse

European Journal Of Medicinal Chemistry - 15/3/2020

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2020.112090 View at source

  • ISSN 02235234
  • ISSN/ISBN 1768-3254

Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas

  • Escoll M
  • Lastra D
  • Pajares M
  • Robledinos-Antón N
  • Rojo A
  • Fernández-Ginés R
  • Mendiola M
  • Martínez-Marín V
  • Esteban I
  • López-Larrubia P
  • Gargini R
  • Cuadrado A
... View more Collapse

Redox Biology - 1/2/2020

10.1016/j.redox.2019.101425 View at source

  • ISSN 22132317

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

  • Robledinos-Anton, Natalia
  • Fernandez-Gines, Raquel
  • Manda, Gina
  • Cuadrado, Antonio;

Oxidative Medicine And Cellular Longevity - 1/1/2019

10.1155/2019/9372182 View at source

  • ISSN 19420900

This researcher has no books.

Perspectives on the Clinical Development of NRF2-Targeting Drugs

  • Lastra D
  • Fernández-Ginés R
  • Manda G
  • Cuadrado A

Handbook Of Experimental Pharmacology (p. 93-141) - 1/1/2021

10.1007/164_2020_381 View at source

  • ISSN 01712004

TARGETING THE NRF2/BETATRCP AXIS IN LIVER DISEASE

  • Cuadrado, A
  • Rojo, AI
  • Fernandez-Gines, R

Free Radical Biology And Medicine (p. 10-10) - 20/8/2022

  • ISSN 08915849
  • iMarina

An inhibitor of the NRF2-beta TrCP interaction suppresses lipopolysaccharid-mediated inflammation in vitro and in vivo

  • Fernandez-Gines, Raquel
  • Rojo, Ana I.
  • Antonio Encinar, Jose
  • Wells, Geoffrey
  • Cuadrado, Antonio;

FREE RADICAL BIOLOGY AND MEDICINE - 1/1/2021

10.1016/j.freeradbiomed.2020.12.298 View at source

  • ISSN 08915849

This researcher has no working papers.

This researcher has no technical reports.

PAPEL DEL FACTOR DE TRANSCRIPCIÓN NRF2 EN PROTECCIÓN SINÁPTICA EN LAS TAUOPATÍAS

  • FERNANDEZ GINES, RAQUEL (Investigador/a)
  • JIMENEZ VILLEGAS, JOSE (Investigador/a)
  • CARNICERO SENABRE, DANIEL (Investigador/a)
  • Escoll Guerrero, Maria Isabel (Investigador/a)
  • GARCIA YAGUE, ANGEL JUAN (Investigador/a)
  • CAZALLA IBAÑEZ, EDUARDO (Investigador/a)
  • Rojo Sanchís, Ana Isabel (Investigador principal (IP))
  • Cuadrado Pastor, Antonio (Investigador principal (IP))
... View more Collapse

Period: 01-09-2023 - 31-08-2026

Type of funding: National

Amount of funding: 375000,00 Euros.

  • iMarina

OPTIMIZACIÓN DE UN NUEVO ACTIVADOR DEL FACTOR DE TRANSCRIPCIÓN NRF2 PARA FRENAR LA PROGRESIÓN DE NASH

  • FERNANDEZ GINES, RAQUEL (Investigador/a)
  • GARCIA YAGUE, ANGEL JUAN (Investigador/a)
  • Rojo Sanchís, Ana Isabel (Investigador principal (IP))
  • Cuadrado Pastor, Antonio (Investigador principal (IP))

Period: 01-12-2022 - 30-11-2024

Type of funding: National

Amount of funding: 149500,00 Euros.

  • iMarina

El factor de transcripción nrf2 en la patofisiología de la enfermedad de Alzheimer

  • Pajares Cabetas, Marta (Investigador/a)
  • GARCIA YAGUE, ANGEL JUAN (Investigador/a)
  • FERNANDEZ GINES, RAQUEL (Investigador/a)
  • LASTRA MARTINEZ, DIEGO (Investigador/a)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))
  • Robledinos Anton, Natalia (Investigador/a)
  • Escoll Guerrero, Maria Isabel (Investigador/a)
  • Rojo Sanchís, Ana Isabel (Investigador principal (IP))
... View more Collapse

Period: 01-06-2020 - 31-05-2023

Type of funding: National

Amount of funding: 369050,00 Euros.

  • iMarina

This researcher has no supervised thesis.

Treatment of NRF2-related diseases

  • Cuadrado Pastor, Antonio (Autor o Coautor)
  • FERNANDEZ GINES, RAQUEL (Autor o Coautor)
  • Leon Martinez, Rafael (Autor o Coautor)
  • FRANCO GONZALEZ, JUAN FELIPE (Autor o Coautor)
  • Garcia Lopez, Manuela (Autor o Coautor)
  • Rojo Sanchís, Ana Isabel (Autor o Coautor)

21/7/2022

  • iMarina

Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-BETA-TRCP interaction for use in the treatment of fatty liver disease

  • Rojo Sanchís, Ana Isabel (Autor o Coautor)
  • RODRIGUEZ FRANCO, Maria Isabel (Autor o Coautor)
  • Garcia Lopez, Manuela (Autor o Coautor)
  • FRANCO GONZALEZ, JUAN FELIPE (Autor o Coautor)
  • FERNANDEZ GINES, RAQUEL (Autor o Coautor)
  • Leon Martinez, Rafael (Autor o Coautor)
  • ENCINAR, JOSÉ ANTONIO (Autor o Coautor)
  • Cuadrado Pastor, Antonio (Autor o Coautor)
... View more Collapse

13/1/2022

  • iMarina
Last data update: 8/12/24 1:27 PM