Morphine self-administration alters the expression of translational machinery genes in the amygdala of male Lewis rats - Ucha, M.; Coria, S.M.; Núñez, A.E.; Santos-Toscano, R.; Roura-Martínez, D.; Fernández-Ruiz, J.; Higuera-Matas, A.; Ambrosio, E. (JOURNAL OF PSYCHOPHARMACOLOGY, 2019)

Behavioral and molecular changes elicited by acute administration of SR141716 to ?9-tetrahydrocannabinol-tolerant rats: An experimental model of cannabinoid abstinence - González, S.; Fernández-Ruiz, J.; Di Marzo, V.; Hernández, M.; Arévalo, C.; Nicanor, C.; Cascio, M.G.; Ambrosio, E.; Ramos, J.A. (DRUG AND ALCOHOL DEPENDENCE, 2004)

Effects of perinatal exposure to ?9-tetrahydrocannabinol on operant morphine-reinforced behavior - González, B.; De Miguel, R.; Martín, S.; Pérez-Rosado, A.; Romero, J.; García-Lecumberri, C.; Fernández-Ruiz, J.; Ramos, J.A.; Ambrosio, E. (Pharmacology Biochemistry And Behavior, 2003)

Maternal exposure to Delta(9)-tetrahydrocannabinol facilitates morphine self-administration behavior and changes regional binding to central mu opioid receptors in adult offspring female rats - Vela, G.; Martín, S.; García-Gil, L.; Crespo, J.A.; Ruiz-Gayo, M.; Javier Fernández-Ruiz, J.; García-Lecumberri, C.; Pélaprat, D.; Fuentes, J.A.; Ramos, J.A.; Ambrosio, E. (BRAIN RESEARCH, 1998)

Sex-dependent changes in brain CB1R expression and functionality and immune CB2R expression as a consequence of maternal deprivation and adolescent cocaine exposure - Llorente-Berzal, Alvaro; Assis, Maria A; Rubino, Tiziana; Zamberletti, Erica; Marco, Eva M; Parolaro, Daniela; Ambrosio, Emilio; Viveros, Maria-Paz (Pharmacological Research, 2013)

Mu-Opioid Receptors in Ganglia, But Not in Muscle, Mediate Peripheral Analgesia in Rat Muscle Pain - Bagues, A.; Martín, M.I.; Higuera-Matas, A.; Esteban-Hernández, J.; Ambrosio, E.; María Sánchez-Robles, E. (Anesthesia And Analgesia, 2018)

Chronic Cannabinoid Administration to Periadolescent Rats Modulates the Metabolic Response to Acute Cocaine in the Adult Brain (vol 13, pg 411, 2011) - Higuera-Matas, A.; Soto-Montenegro, M.L.; Montoya, G.L.; García-Vázquez, V.; Pascau, J.; Migúns, M.; Del Olmo, N.; Vaquero, J.J.; García-Lecumberri, C.; Desco, M.; Ambrosio, E. (Molecular Imaging And Biology, 2011)

Chronic Cannabinoid Administration to Periadolescent Rats Modulates the Metabolic Response to Acute Cocaine in the Adult Brain - Higuera-Matas, A.; Soto-Montenegro, M.L.; Montoya, G.L.; García-Vázquez, V.; Pascau, J.; Miguéns, M.; Del Olmo, N.; Vaquero, J.J.; García-Lecumberri, C.; Desco, M.; Ambrosio, E. (Molecular Imaging And Biology, 2011)

Consensus document on the approach to addiction from the neuroscience perspectives [Documento de consenso para el abordaje de las adicciones desde las neurociencias] - E.A. Flores; C. Aragón Cancela; J. Chicharro Romero; D. Ezpeleta; E. Fernández Espejo; G. García Fernández; O. García Rodríguez; J. González Menacho; I. Iraurgi; N. Landa González; M. Llanero Luque; M.Á. Lloves Moratinos; et al. (Trastornos Adictivos, 2009)

Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3,4-methylenedioxymethamphetamine, "ecstasy") exhibit increased ethanol consumption and preference - Izco, M.; Marchant, I.; Escobedo, I.; Peraile, I.; Delgado, M.; Higuera-Matas, A.; Olias, O.; Ambrosio, E.; O'Shea, E.; Colado, M.I. (Journal of Pharmacology and Experimental Therapeutics, 2007)

Morphine self-administration effects on the structure of cortical pyramidal cells in addiction-resistant rats - Ballesteros-Yanez, I.; Ambrosio, E.; Pérez, J.; Torres, I.; Miguéns, M.; García-Lecumberri, C.; DeFelipe, J. (Brain Research, 2008)

Extinction of cocaine self-administration produces a differential time-related regulation of proenkephalin gene expression in rat brain - Crespo, J.A.; Manzanares, J.; Oliva, J.M.; Corchero, J.; Palomo, T.; Ambrosio, E. (Neuropsychopharmacology, 2001)

Involvement of 5-HT1A receptors in behavioural effects of the cannabinoid receptor agonist CP 55,940 in male rats - Marco, E.M.; Pérez-Alvarez, L.; Borcel, E.; Rubio, M.; Guaza, C.; Ambrosio, E.; File, S.E.; Viveros, M.P. (Behavioural Pharmacology, 2004)

Chronic treatment with CP 55,940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood - Biscaia, M.; Marín, S.; Fernández, B.; Marco, E.M.; Rubio, M.; Guaza, C.; Ambrosio, E.; Viveros, M.P. (Psychopharmacology, 2003)

Cocaine self-administration differentially modulates the expression of endogenous cannabinoid system-related proteins in the hippocampus of Lewis vs. Fischer 344 rats - Rivera, P.; Miguéns, M.; Coria, S.M.; Rubio, L.; Higuera-Matas, A.; Bermúdez-Silva, F.J.; De Fonseca, F.R.; Suárez, J.; Ambrosio, E. (International Journal of Neuropsychopharmacology, 2013)

The effects of combined intravenous cocaine and ethanol self-administration on the behavioral and amino acid profile of young adult rats - Marcos, A.; Moreno, M.; Orihuel, J.; Ucha, M.; De Paz, A.M.; Higuera-Matas, A.; Capellán, R.; Crego, A.L.; Martínez-Larrañaga, M.-R.; Ambrosio, E.; Anadón, A. (PLoS ONE, 2020)

MouBeAT: A new and open toolbox for guided analysis of behavioral tests in mice - Bello-Arroyo, E.; Roque, H.; Marcos, A.; Orihuel, J.; Higuera-Matas, A.; Desco, M.; Caiolfa, V.R.; Ambrosio, E.; Lara-Pezzi, E.; Gómez-Gaviro, M.V. (Frontiers in Behavioral Neuroscience, 2018)

Augmented acquisition of cocaine self-administration and altered brain glucose metabolism in adult female but not male rats exposed to a cannabinoid agonist during adolescence - Higuera-Matas, A.; Luisa Soto-Montenegro, M.; Del Olmo, N.; Miguéns, M.; Torres, I.; José Vaquero, J.; Sánchez, J.; García-Lecumberri, C.; Desco, M.; Ambrosio, E. (Neuropsychopharmacology, 2008)

Central nucleus of the amygdala as a common substrate of the incubation of drug and natural reinforcer seeking - Roura-Martínez, D.; Ucha, M.; Orihuel, J.; Ballesteros-Yáñez, I.; Castillo, C.A.; Marcos, A.; Ambrosio, E.; Higuera-Matas, A. (Addiction Biology, 2020)

Vulnerabilidad a lo drogadicción - Ambrosio Flores, Emilio (100cias UNED, 2000)

¿Son reversibles los efectos neurotóxicos de las drogas de síntesis? - Ambrosio Flores, Emilio (Adicciones: Revista de socidrogalcohol, 2006)

Efectos de la cocaína en el ser humano - Ambrosio Flores, Emilio (Trastornos adictivos: Organo Oficial de la Sociedad española de Toxicomanías, 2008)

Conducta impulsiva y vulnerabilidad a la adicción a opiaceos - Torres,I; Crespo,J A; García-Lecumberri,C; Ambrosio,E (Trastornos adictivos: Organo Oficial de la Sociedad española de Toxicomanías, 2001)

Changes in D1 but not D2 dopamine or mu-opioid receptor expression in limbic and motor structures after lateral hypothalamus electrical self-stimulation: A quantitative autoradiographic study - Simon, M.J.; Higuera-Matas, A.; Roura-Martinez, D.; Ucha-Tortuero, M.; Santos-Toscano, R.; Garcia-Lecumberri, C.; Ambrosio, E.; Puerto, A. (Neurobiology of Learning and Memory, 2016)

Strain differences in the expression of endocannabinoid genes and in cannabinoid receptor binding in the brain of Lewis and Fischer 344 rats - Coria, S.M.; Roura-Martínez, D.; Ucha, M.; Assis, M.A.; Miguéns, M.; García-Lecumberri, C.; Higuera-Matas, A.; Ambrosio, E. (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2014)

Strain differences in the dose-response relationship for morphine self-administration and impulsive choice between Lewis and Fischer 344 rats - García-Lecumberri, C.; Torres, I.; Martín, S.; Crespo, J.A.; Miguéns, M.; Nicanor, C.; Higuera-Matas, A.; Ambrosio, E. (Journal of Psychopharmacology, 2011)

Differential gene expression in the nucleus accumbens and frontal cortex of Lewis and Fischer 344 rats relevant to drug addiction - Higuera-Matas, A.; Montoya, G.L.; Coria, S.M.; Miguéns, M.; García-Lecumberri, C.; Ambrosio, E. (Current Neuropharmacology, 2011)

Neural changes developed during the extinction of cocaine self-administration behavior - Higuera-Matas, A.; Miguens, M.; del Olmo, N.; García-Lecumberri, C.; Ambrosio, E. (Pharmaceuticals, 2011)

Periadolescent exposure to cannabinoids alters the striatal and hippocampal dopaminergic system in the adult rat brain - Higuera-Matas, A.; Botreau, F.; Del Olmo, N.; Miguéns, M.; Olías, O.; Montoya, G.L.; García-Lecumberri, C.; Ambrosio, E. (European Neuropsychopharmacology, 2010)

Chronic periadolescent cannabinoid treatment enhances adult hippocampal PSA-NCAM expression in male Wistar rats but only has marginal effects on anxiety, learning and memory - Higuera-Matas, A.; Botreau, F.; Miguéns, M.; Del Olmo, N.; Borcel, E.; Pérez-Álvarez, L.; García-Lecumberri, C.; Ambrosio, E. (Pharmacology Biochemistry and Behavior, 2009)

Strain differences between Lewis and Fischer 344 rats in the modulation of dopaminergic receptors after morphine self-administration and during extinction - Sánchez-Cardoso, P.; Higuera-Matas, A.; Martín, S.; Miguéns, M.; Del Olmo, N.; García-Lecumberri, C.; Ambrosio, E. (Neuropharmacology, 2009)

Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration - Miguéns, M.; Crespo, J.A.; Del Olmo, N.; Higuera-Matas, A.; Montoya, G.L.; García-Lecumberri, C.; Ambrosio, E. (Neuropharmacology, 2008)

Sex-dependent effects of periadolescent exposure to the cannabinoid agonist CP-55,940 on morphine self-administration behaviour and the endogenous opioid system - Biscaia, M.; Fernández, B.; Higuera-Matas, A.; Miguéns, M.; Viveros, M.-P.; García-Lecumberri, C.; Ambrosio, E. (Neuropharmacology, 2008)

Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: A time course microdialysis study - Miguéns, M.; Del Olmo, N.; Higuera-Matas, A.; Torres, I.; García-Lecumberri, C.; Ambrosio, E. (Psychopharmacology, 2008)

Toluene and TCE decrease binding to mu-opioid receptors, but not to benzodiazepine and NMDA receptors in mouse brain - Páez-Martínez, N.; Ambrosio, E.; García-Lecumberri, C.; Rocha, L.; Montoya, G.L.; Cruz, S.L. (Annals of the New York Academy of Sciences, 2008)

Cocaine self-administration improves performance in a highly demanding water maze task - Del Olmo, N.; Higuera-Matas, A.; Miguéns, M.; García-Lecumberri, C.; Ambrosio, E. (Psychopharmacology, 2007)

Modulation of the endogenous opioid system after morphine self-administration and during its extinction: A study in Lewis and Fischer 344 rats - Sánchez-Cardoso, P.; Higuera-Matas, A.; Martín, S.; del Olmo, N.; Miguéns, M.; García-Lecumberri, C.; Ambrosio, E. (Neuropharmacology, 2007)

The effects of morphine self-administration on cortical pyramidal cell structure in addiction-prone lewis rats - Ballesteros-Yáñez, I.; Ambrosio, E.; Benavides-Piccione, R.; Pérez, J.; Torres, I.; Miguéns, M.; García-Lecumberri, C.; DeFelipe, J. (Cerebral Cortex, 2007)

Enhancement of hippocampal long-term potentiation induced by cocaine self-administration is maintained during the extinction of this behavior - del Olmo, N.; Miguéns, M.; Higuera-Matas, A.; Torres, I.; García-Lecumberri, C.; Solís, J.M.; Ambrosio, E. (Brain Research, 2006)

Hippocampal synaptic plasticity and water maze learning in cocaine self-administered rats - Del Olmo, N.; Higuera-Matas, A.; Miguéns, M.; García-Lecumberri, C.; Borcel, E.; Solís, J.M.; Ambrosio, E. (Annals of the New York Academy of Sciences, 2006)

Repeated administration with ?9-tetrahydrocannabinol regulates ?-opioid receptor density in the rat brain - Corchero, J.; Oliva, J.M.; García-Lecumberri, C.; Martin, S.; Ambrosio, E.; Manzanares, J. (Journal of Psychopharmacology, 2004)

Extinction of cocaine self-administration produces alterations in corticotropin releasing factor gene expression in the paraventricular nucleus of the hypothalamus - Crespo, J.A.; Manzanares, J.; Oliva, J.M.; Corchero, J.; García-Lecumberri, C.; Ambrosio, E. (Molecular Brain Research, 2003)

Genetic differences in NMDA and D1 receptor levels, and operant responding for food and morphine in Lewis and Fischer 344 rats - Martín, S.; Lyupina, Y.; Crespo, J.A.; González, B.; García-Lecumberri, C.; Ambrosio, E. (Brain Research, 2003)

Differential effect of low doses of intracerebroventricular corticotropin-releasing factor in forced swimming test - García-Lecumberri, C.; Ambrosio, E. (Pharmacology Biochemistry and Behavior, 2000)

The neurobiology of cannabinoid dependence: Sex differences and potential interactions between cannabinoid and opioid systems - Ambrosio, E.; Martín, S.; García-Lecumberri, C.; Crespo, J.A. (Life Sciences, 1999)

Differential basal proenkephalin gene expression in dorsal striatum and nucleus accumbens, and vulnerability to morphine self-administration in Fischer 344 and Lewis rats - Martín, S.; Manzanares, J.; Corchero, J.; García-Lecumberri, C.; Crespo, J.A.; Fuentes, J.A.; Ambrosio, E. (Brain Research, 1999)

Role of corticotropin-releasing factor in forced swimming test - García-Lecumberri, C.; Ambrosio, E. (European Journal of Pharmacology, 1998)

Effect of yohimbine on the development of morphine dependence in the rat: Lack of involvement of cortical ?-adrenoceptor modifications - Ambrosio, E.; Iglesias, V.; García-Lecumberri, C.; Orensanz, L.; Alguacil, L.F. (Pharmacology Biochemistry and Behavior, 1997)

Individual differences in schedule-induced polydipsia: Neuroanatomical dopamine divergences - Pellón, R.; Ruíz, A.; Moreno, M.; Claro, F.; Ambrosio, E.; Flores, P. (Behavioural Brain Research, 2011)

Comparative analysis of the modulation of perineuronal nets in the prefrontal cortex of rats during protracted withdrawal from cocaine, heroin and sucrose self-administration - Roura-Martínez, D.; Díaz-Bejarano, P.; Ucha, M.; Paiva, R.R.; Ambrosio, E.; Higuera-Matas, A. (Neuropharmacology, 2020)

Maternal immune activation is associated with a lower number of dopamine receptor 3-expressing granulocytes with no alterations in cocaine reward, resistance to extinction or cue-induced reinstatement - Santos-Toscano, R.; Ucha, M.; Borcel, É.; Ambrosio, E.; Higuera-Matas, A. (Pharmacology Biochemistry and Behavior, 2020)

Impulsive action and impulsive choice are differentially associated with gene expression variations of the GABAA receptor alfa 1 subunit and the CB1 receptor in the lateral and medial orbitofrontal cortices - Ucha, M.; Roura-Martínez, D.; Contreras, A.; Pinto-Rivero, S.; Orihuel, J.; Ambrosio, E.; Higuera-Matas, A. (Frontiers in Behavioral Neuroscience, 2019)

Selective effects of ?9-tetrahydrocannabinol on medium spiny neurons in the striatum - Fernández-Cabrera, M.R.; Higuera-Matas, A.; Fernaud-Espinosa, I.; DeFelipe, J.; Ambrosio, E.; Miguéns, M. (PLoS ONE, 2018)

Investigation on the combined effect of cocaine and ethanol administration through a liquid chromatography?mass spectrometry metabolomics approach - Sánchez-López, E.; Marcos, A.; Ambrosio, E.; Mayboroda, O.A.; Marina, M.L.; Crego, A.L. (Journal of Pharmaceutical and Biomedical Analysis, 2017)

Lewis and Fischer 344 rats as a model for genetic differences in spatial learning and memory: Cocaine effects - Fole, A.; Miguéns, M.; Morales, L.; González-Martín, C.; Ambrosio, E.; Del Olmo, N. (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2017)

Extended-access methamphetamine self-administration elicits neuroinflammatory response along with blood-brain barrier breakdown - Gonçalves, J.; Leitão, R.A.; Higuera-Matas, A.; Assis, M.A.; Coria, S.M.; Fontes-Ribeiro, C.; Ambrosio, E.; Silva, A.P. (Brain, Behavior, and Immunity, 2017)

Parafascicular thalamic nucleus deep brain stimulation decreases NMDA receptor GluN1 subunit gene expression in the prefrontal cortex - Fernández-Cabrera, M.R.; Selvas, A.; Miguéns, M.; Higuera-Matas, A.; Vale-Martínez, A.; Ambrosio, E.; Martí-Nicolovius, M.; Guillazo-Blanch, G. (Neuroscience, 2017)

Strain differences in cannabinoid-reinforced lever press discrimination - Coria, S.M.; Roura-Martínez, D.; Ucha, M.; Orihuel, J.; Higuera-Matas, A.; Ambrosio, E. (Journal of Drug and Alcohol Research, 2017)

Rat-strain dependent changes of dendritic and spine morphology in the hippocampus after cocaine self-administration - Selvas, A.; Coria, S.M.; Kastanauskaite, A.; Fernaud-Espinosa, I.; DeFelipe, J.; Ambrosio, E.; Miguéns, M. (Addiction Biology, 2017)

Enantioseparation of the constituents involved in the phenylalanine-tyrosine metabolic pathway by capillary electrophoresis tandem mass spectrometry - Sánchez-López, E.; Marcos, A.; Ambrosio, E.; Marina, M.L.; Crego, A.L. (Journal of Chromatography A, 2016)

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia - Santos-Toscano, R.; Borcel, É.; Ucha, M.; Orihuel, J.; Capellán, R.; Roura-Martínez, D.; Ambrosio, E.; Higuera-Matas, A. (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2016)

Decreased rates of operant food self-administration are associated with reward deficits in high-fat feeding mice - Íbias, J.; Miguéns, M.; del Rio, D.; Valladolid-Acebes, I.; Stucchi, P.; Ambrosio, E.; Martín, M.; Morales, L.; Ruiz-Gayo, M.; Del Olmo, N. (European Journal of Nutrition, 2016)

Long-term consequences of perinatal and adolescent cannabinoid exposure on neural and psychological processes - Higuera-Matas, A.; Ucha, M.; Ambrosio, E. (Neuroscience and Biobehavioral Reviews, 2015)

The effects of cocaine self-administration on dendritic spine density in the rat hippocampus are dependent on genetic background - Miguéns, M.; Kastanauskaite, A.; Coria, S.M.; Selvas, A.; Ballesteros-Yañez, I.; DeFelipe, J.; Ambrosio, E. (Cerebral Cortex, 2015)

Cocaine facilitates protein synthesis-dependent LTP: The role of metabotropic glutamate receptors - Fole, A.; Miguens, M.; Higuera-Matas, A.; Alguacil, L.F.; Ambrosio, E.; Del Olmo, N. (European Neuropsychopharmacology, 2014)

Genetic differences in the modulation of accumbal glutamate and ?-amino butyric acid levels after cocaine-induced reinstatement - Miguéns, M.; Botreau, F.; Olías, O.; Del Olmo, N.; Coria, S.M.; Higuera-Matas, A.; Ambrosio, E. (Addiction Biology, 2013)

CNR1 gene deletion affects the density of endomorphin-2 binding sites in the mouse brain in a hemisphere-specific manner - Paldy, E.; Borcel, E.; Higuera-Matas, A.; López-Montoya, G.; Wenger, T.; Toth, G.; Borsodi, A.; Ambrosio, E. (European Journal of Pharmacology, 2013)

Sex-specific disturbances of the glutamate/GABA balance in the hippocampus of adult rats subjected to adolescent cannabinoid exposure - Higuera-Matas, A.; Miguéns, M.; Coria, S.M.; Assis, M.A.; Borcel, E.; Del Olmo, N.; Ambrosio, E. (Neuropharmacology, 2012)

Immunoglobulin G Fc receptor deficiency prevents Alzheimer-like pathology and cognitive impairment in mice - Fernandez-Vizarra, P; Lopez-Franco, O; Mallavia, B; Higuera-Matas, A; Lopez-Parra, V; Ortiz-Muñoz, G; Ambrosio, E; Egido, J; Almeida, OFX; Gomez-Guerrero, C (Brain, 2012)

Depotentiation of hippocampal long-term potentiation depends on genetic background and is modulated by cocaine self-administration - Miguéns, M.; Coria, S.M.; Higuera-Matas, A.; Fole, A.; Ambrosio, E.; Del Olmo, N. (Neuroscience, 2011)

Effects of chronic cocaine administration on spatial learning and hippocampal spine density in two genetically different strains of rats - Fole, A.; González-Martín, C.; Huarte, C.; Alguacil, L.F.; Ambrosio, E.; Olmo, N.D. (Neurobiology of Learning and Memory, 2011)

Genetic differences in hippocampal synaptic plasticity - Prakash, S.; Ambrosio, E.; Alguacil, L.F.; del Olmo, N. (Neuroscience, 2009)

HPA axis function and drug addictive behaviors: Insights from studies with Lewis and Fischer 344 inbred rats - Kosten, T.A.; Ambrosio, E. (Psychoneuroendocrinology, 2002)

Neuroadaptive changes in NMDAR1 gene expression after extinction of cocaine self-administration - Crespo, J.A.; Oliva, J.M.; Ghasemzadeh, M.B.; Kalivas, P.W.; Ambrosio, E. (Annals of the New York Academy of Sciences, 2002)

Differential neuroendocrine responsiveness to morphine in Lewis, Fischer 344, and ACI inbred rats - Baumann, M.H.; Elmer, G.I.; Goldberg, S.R.; Ambrosio, E. (Brain Research, 2000)

Cerebral glucose metabolism during opioid withdrawal following methylnaloxonium injection into the locus coeruleus - Kimes, A.S.; Maldonado, R.; Ambrosio, E.; Koob, G.F.; London, E.D. (Brain Research, 1998)

Role of corticotropin-releasing hormone in gastrin-releasing peptide-mediated regulation of corticotropin and corticosterone secretion in male rats - Garrido, M.M.; Martin, S.; Ambrosio, E.; Fuentes, J.A.; Manzanares, J. (Neuroendocrinology, 1998)

Medial prefrontal cortical injections of c-Fos antisense oligonucleotides transiently lower c-fos protein and mimic amphetamine withdrawal behaviours - Persico, A.M.; Schindler, C.W.; Davis, S.C.; Ambrosio, E.; Uhl, G.R. (Neuroscience, 1997)

Regional binding to corticotropin releasing factor receptors in brain of rats exposed to chronic cocaine and cocaine withdrawal - Ambrosio, E.; Sharpe, L.G.; Pilotte, N.S. (Synapse, 1997)

Cardiovascular effects of cocaine during operant cocaine self-administration - Ambrosio, E.; Tella, S.R.; Goldberg, S.R.; Schindler, C.W.; Erzouki, H.; Elmer, G.I. (European Journal of Pharmacology, 1996)

Behavior genetic investigation of the relationship between spontaneous locomotor activity and the acquisition of morphine self-administration behavior - Ambrosio, E.; Goldberg, S.R.; Elmer, G.I. (Behavioural Pharmacology, 1995)

The epileptogenic action of the taurine analogue guanidinoethane sulfonate may be caused by a blockade of GABA receptors - Herranz, A.S.; Solis, J.M.; Herreras, O.; Menéndez, N.; Ambrosio, E.; Orensanz, L.M.; del Rio, R.M. (Journal of Neuroscience Research, 1990)

A re-examination of the Na+-independent binding of [3H]?-alanine to rat brain stem-spinal cord - Orensanz, L.M.; Ambrosio, E.; Fernández, I.; Montero, M.T. (Neurochemical Research, 1988)

[3H]prazosin binding to central nervous system regions of male and female rats - Ambrosio, E.; Montero, M.T.; Fernandez, I.; Azuara, M.C.; Orensanz, L.M. (Neuroscience Letters, 1984)

Sex differences in alpha-adrenergic receptors in the rat brain - Orensanz, L.M.; Guillamon, A.; Ambrosio, E.; Segovia, S.; Azuara, M.C. (Neuroscience Letters, 1982)

The role of the mTOR pathway in models of drug-induced reward and the behavioural constituents of addiction - Ucha, M.; Roura-Martínez, D.; Ambrosio, E.; Higuera-Matas, A. (Journal of Psychopharmacology, 2020)

Transplantation with Lewis bone marrow induces the reinstatement of cocaine-seeking behavior in male F344 resistant rats - Assis, M.A.; Díaz, D.; Ferrado, R.; Ávila-Zarza, C.A.; Weruaga, E.; Ambrosio, E. (Brain, Behavior, and Immunity, 2021)

3D Synaptic Organization of the Rat CA1 and Alterations Induced by Cocaine Self-Administration - Blazquez-Llorca, L.; Miguéns, M.; Montero-Crespo, M.; Selvas, A.; Gonzalez-Soriano, J.; Ambrosio, E.; DeFelipe, J. (Cerebral cortex (New York, N.Y. : 1991), 2021)

Cocaine-induced Fos expression in the rat brain: Modulation by prior ?9-tetrahydrocannabinol exposure during adolescence and sex-specific effects - Orihuel, J.; Gómez-Rubio, L.; Valverde, C.; Capellán, R.; Roura-Martínez, D.; Ucha, M.; Ambrosio, E.; Higuera-Matas, A. (Brain Research, 2021)

A ?drug-dependent? immune system can compromise protection against infection: The relationships between psychostimulants and hiv - Assis, M.A.; Carranza, P.G.; Ambrosio, E. (Viruses, 2021)

Ex vivo 1H-MRS brain metabolic profiling in a two-hit model of neurodevelopmental disorders: Prenatal immune activation and peripubertal stress - Capellán, R.; Moreno-Fernández, M.; Orihuel, J.; Roura-Martínez, D.; Ucha, M.; Ambrosio, E.; Higuera-Matas, A. (Schizophrenia Research, 2022)

? 9-Tetrahydrocannabinol during adolescence reprograms the nucleus accumbens transcriptome, affecting reward processing, impulsivity, and specific aspects of cocaine addiction-like behavior in a sex-dependent manner - Orihuel, J.; Capellán, R.; Roura-Martínez, D.; Ucha, M.; Ambrosio, E.; Higuera-Matas, A. (International Journal of Neuropsychopharmacology, 2021)

The interactions of alcohol and cocaine regulate the expression of genes involved in the GABAergic, glutamatergic and endocannabinoid systems of male and female rats - Marcos, A.; Ballesteros-Yáñez, I.; Castillo-Sarmiento, C.A.; Pardo, F.; Roura-Martínez, D.; Muñoz-Rodríguez, J.R.; Higuera-Matas, A.; Ambrosio, E. (Neuropharmacology, 2022)

Neuroimaging reveals distinct brain glucose metabolism patterns associated with morphine consumption in Lewis and Fischer 344 rat strains - Soto-Montenegro, M.ªL.; García-Vázquez, V.; Lamanna-Rama, N.; López-Montoya, G.; Desco, M.; Ambrosio, E. (Scientific Reports, 2022)

Effects of heroin self-administration and forced withdrawal on the expression of genes related to the mTOR network in the basolateral complex of the amygdala of male Lewis rats - Ucha, M.; Roura-Martínez, D.; Santos-Toscano, R.; Capellán, R.; Ambrosio, E.; Higuera-Matas, A. (Psychopharmacology, 2022)

Transferrin analysis in wistar rats plasma: Towards an electrochemical point-of-care approach for the screening of alcohol abuse - Rodriguez-Hidalgo, G.; Sierra, T.; Dortez, S.; Marcos, A.; Ambrosio, E.; Crevillen, A.G.; Escarpa, A. (Microchemical Journal, 2022)

Plasma Amino Acid Concentrations in Patients with Alcohol and/or Cocaine Use Disorders and Their Association with Psychiatric Comorbidity and Sex - García-Marchena, N.; Marcos, A.; Flores-López, M.; Moreno-Fernández, M.; Requena-Ocaña, N.; Porras-Perales, O.; Torres-Galván, S.; Araos, P.; Serrano, A.; Muga, R.; Ruiz-Ruiz, J.J.; de Fonseca, F.R.; et al. (Biomedicines, 2022)

Pharmacological characterization of novel synthetic opioids: Isotonitazene, metonitazene, and piperidylthiambutene as potent ?-opioid receptor agonists - De Luca, M.A.; Tocco, G.; Mostallino, R.; Laus, A.; Caria, F.; Musa, A.; Pintori, N.; Ucha, M.; Poza, C.; Ambrosio, E.; Di Chiara, G.; Castelli, M.P. (Neuropharmacology, 2022)

Saturated and unsaturated triglyceride-enriched diets modify amino acid content in the mice hippocampus - Fernández-Felipe, J.; Sanz-Martos, A.B.; Marcos, A.; Lorenzo, M.P.; Cano, V.; Merino, B.; Ambrosio, E.; Del Olmo, N.; Ruiz-Gayo, M. (Neuroscience Letters, 2023)

Neuroimaging revealed long-lasting glucose metabolism changes to morphine withdrawal in rats pretreated with the cannabinoid agonist CP-55,940 during periadolescence - Lamanna-Rama, N.; MacDowell, K.S.; López, G.; Leza, J.C.; Desco, M.; Ambrosio, E.; Soto-Montenegro, M.L. (European Neuropsychopharmacology, 2023)

Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome - Capellan, Roberto; Orihuel, Javier; Marcos, Alberto; Ucha, Marcos; Moreno-Fernandez, Mario; Casquero-Veiga, Marta; Soto-Montenegro, Maria Luisa; Desco, Manuel; Oteo-Vives, Marta; Ibanez-Moragues, Marta; Magro-Calvo, Natalia; Morcillo, Miguel Angel; et al. (Translational Psychiatry, 2023)

Untargeted metabolomic study by liquid chromatography?mass spectrometry in brain tissues on the effects of combined cocaine and ethanol self-administration in male and female young rats - Marcos, A.; León, C.; Moreno-Fernández, M.; Castro-Rubio, F.; Garrido-Matilla, L.; Nozal, L.; Ambrosio, E.; Crego, A.L. (Journal of Chromatography A, 2023)

Increase in educational inequalities in alcohol-related mortality in Spain during a period of economic growth - Donat, M.; Regidor, E.; Barrio, G.; Ambrosio, E.; Sordo, L.; Guerras, J.M.; Politi, J.; Belza, M.J. (Addiction, 2023)

Lack of interactions between prenatal immune activation and ?9-tetrahydrocannabinol exposure during adolescence in behaviours relevant to symptom dimensions of schizophrenia in rats - Moreno-Fernández, M.; Ucha, M.; Reis-de-Paiva, R.; Marcos, A.; Ambrosio, E.; Higuera-Matas, A. (Progress in neuro-psychopharmacology & biological psychiatry, 2024)

Alcohol consumption and preference in female rats induced by reward downshift reveals sex generality of the modulatory role of physical activity - Castejón, E.; Ambrosio, E.; Pellón, R.; Torres, C. (Behavioural Pharmacology, 2025)

Saturated and unsaturated high-fat diets induce addictive-like behavior in an animal model of operant self-administration - Roca, M.; Íbias, J.; Mohamedi-Ahmed, Y.; Ruiz-Gayo, M.; Ambrosio, E.; Sanz-Martos, A.B.; Del Olmo, N. (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2025)

A Hidden Mark of a Troubled Past: Neuroimaging and Transcriptomic Analyses Reveal Interactive Effects of Maternal Immune Activation and Adolescent THC Exposure Suggestive of Increased Neuropsychiatric Risk - Moreno-Fernández, M.; Luján, V.; Baliyan, S.; Poza, C.; Capellán, R.; de las Heras-Martínez, N.; Morcillo, M.Á.; Oteo, M.; Ambrosio, E.; Ucha, M.; Higuera-Matas, A. (Biological Psychiatry Global Open Science, 2025)

Preclinical Validation of an Electrochemical Sensor for Alcohol Consumption Monitoring in a Polydrug Self-Administration Animal Model - Garrido-Matilla, L.; María-Hormigos, R.; Monago-Maraña, O.; Marcos, A.; Ambrosio, E.; Crevillen, A.G. (Chemosensors, 2025)

Simultaneous cocaine and ethanol self-administration promotes a sex-dimorphic pattern in drug-seeking behaviour and alters plasma amino acid profile related to glutamate homeostasis in young adult rats - Garrido-Matilla, L.; Marcos, A.; Puig-Martínez, N.; Ambrosio, E. (Pharmacology Biochemistry and Behavior, 2025)

Combined administration of cocaine and alcohol alters the expression of brain peptide/protein profiles in rats: a MALDI imaging mass spectrometry approach - Marcos,A.; Alberdi,P.; Castillo-Sarmiento,C.A.; Ambrosio,E.; Ballesteros-Yáñez,I. (Neurochemistry International, 2025)

Metabolomic profiling of cocaine plus ethanol poly-consumption in young adult rats: Insights into the incubation of drug seeking - Garrido-Matilla,L.; Marcos,A.; León,C.; Nozal,L.; Puig-Martínez,N.; Crego,A.L.; Ambrosio,E. (European Journal of Pharmacology, 2026)

Shared and reinforcer-specific alterations in the CRH and noradrenergic systems following short- and long-term withdrawal from cocaine, heroin, and sucrose self-administration - Roura-Martínez,D.; Ucha,M.; Moreno-Fernández,M.; Castillo,C.A.; Ballesteros-Yáñez,I.; Marcos,A.; Ambrosio,E.; Higuera-Matas,A. (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2026)

Sex differences in hippocampal and prefrontal gene expression of endocannabinoid, glutamatergic and GABAergic systems and amino acids profile underlie cocaine plus ethanol seeking incubation - Garrido-Matilla,L.; Vera-Fernández,C.; Puig-Martínez,N.; Spano,E.; Marcos,A.; Ambrosio,E. (Neuropharmacology, 2026)

Documento de consenso para el abordaje de las adicciones desde las neurociencias - Emilio Ambrosio Flores; Juan Chicharro Romero; David Ezpeleta Echevarri; Emilio Fernández-Espejo; Gloria García Fernández; Olaya García Rodríguez; Ioseba Iraurgi Castillo; Natalia Landa González; Marcos Llanero Luque; Manuel Lloves Moratinos; Ana López Durán; Iñaki Lorea Conde; et al. (2009)