omega-6 polyunsaturated fatty acid gamma-linolenic acid (18 : 3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells - Menendez, JA; Colomer, R; Lupu, R (International Journal Of Cancer, 2004)