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Lucio Ortega, Héctor Elessar de

Química Orgánica y Química Inorgánica / Universidad de Alcalá

Publications

Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability

  • Ruiz-Santaquiteria, M.
  • de Castro, S.
  • Toro, M.A.
  • de Lucio, H.
  • Gutiérrez, K.J.
  • Sánchez-Murcia, P.A.
  • Jiménez, M.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Camarasa, M.-J.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry (p. 238-247) - 2018

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2018.02.071 View at source

  • ISSN/ISBN 1768-3254

Synthesis and leishmanicidal activity of novel urea, thiourea, and selenourea derivatives of diselenides

  • Díaz, M.
  • de Lucio, H.
  • Moreno, E.
  • Espuelas, S.
  • Aydillo, C.
  • Jiménez-Ruiz, A.
  • Toro, M.Á.
  • Gutiérrez, K.J.
  • Martínez-Merino, V.
  • Cornejo, A.
  • Palop, J.A.
  • Sanmartín, C.
  • Planoa, D.
... View more Collapse

Antimicrobial Agents and Chemotherapy - 2019

Editor: American Society for Microbiology

10.1128/aac.02200-18 View at source

  • ISSN/ISBN 1098-6596

Small molecule–peptide conjugates as dimerization inhibitors of leishmania infantum trypanothione disulfide reductase

  • Revuelto, A.
  • López-Martín, I.
  • de Lucio, H.
  • García-Soriano, J.C.
  • Zanda, N.
  • de Castro, S.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Velázquez, S.
  • Camarasa, M.-J.
... View more Collapse

Pharmaceuticals - 2021

Editor: MDPI AG

10.3390/ph14070689 View at source

  • ISSN/ISBN 1424-8247

Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase

  • Revuelto, A.
  • Ruiz-Santaquiteria, M.
  • De Lucio, H.
  • Gamo, A.
  • Carriles, A.A.
  • Gutiérrez, K.J.
  • Sánchez-Murcia, P.A.
  • Hermoso, J.A.
  • Gago, F.
  • Camarasa, M.-J.
  • Jiménez-Ruiz, A.
  • Velázquez, S.
... View more Collapse

ACS Infectious Diseases (p. 873-891) - 2019

Editor: American Chemical Society

10.1021/acsinfecdis.8b00355 View at source

  • ISSN/ISBN 2373-8227

Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase

  • de Lucio, H.
  • García-Marín, J.
  • Sánchez-Alonso, P.
  • García-Soriano, J.C.
  • Toro, M.Á.
  • Vaquero, J.J.
  • Gago, F.
  • Alajarín, R.
  • Jiménez-Ruiz, A.
... View more Collapse

European Journal of Medicinal Chemistry - 2022

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2021.113915 View at source

  • ISSN/ISBN 1768-3254

Pseudoirreversible slow-binding inhibition of trypanothione reductase by a protein–protein interaction disruptor

  • de Lucio, H.
  • Toro, M.A.
  • Camarasa, M.-J.
  • Velázquez, S.
  • Gago, F.
  • Jiménez-Ruiz, A.

British Journal of Pharmacology (p. 5163-5176) - 2020

Editor: John Wiley and Sons Inc

10.1111/bph.15250 View at source

  • ISSN/ISBN 1476-5381

Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania

  • Genes, C.M.
  • de Lucio, H.
  • Sánchez-Murcia, P.A.
  • Gago, F.
  • Jiménez-Ruiz, A.

Cell Death and Disease - 2016

Editor: Nature Publishing Group

10.1038/cddis.2016.229 View at source

  • ISSN/ISBN 2041-4889

Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides

  • de Lucio, H.
  • Gamo, A.M.
  • Ruiz-Santaquiteria, M.
  • de Castro, S.
  • Sánchez-Murcia, P.A.
  • Toro, M.A.
  • Gutiérrez, K.J.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Camarasa, M.-J.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry (p. 615-623) - 2017

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2017.09.032 View at source

  • ISSN/ISBN 1768-3254

Identification of NEK3 and MOK as novel targets for lithium

  • Bravo, A.
  • de Lucio, H.
  • Sánchez-Murcia, P.A.
  • Jiménez-Ruiz, A.
  • Petrone, P.M.
  • Gago, F.
  • Cortés Cabrera, A.
... View more Collapse

Chemical Biology and Drug Design (p. 965-969) - 2019

Editor: Blackwell Publishing Ltd

10.1111/cbdd.13487 View at source

  • ISSN/ISBN 1747-0285

Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library

  • Alcón-Calderón, M.
  • de Lucio, H.
  • García-Soriano, J.C.
  • Revuelto, A.
  • de Castro, S.
  • López-Gutiérrez, C.
  • San-Félix, A.
  • Quesada, E.
  • Gago, F.
  • Camarasa, M.-J.
  • Jiménez-Ruiz, A.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry - 2022

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2022.114675 View at source

  • ISSN/ISBN 1768-3254

This researcher has no books.

Investigación en nuevos fármacos frente a COVID-19

  • Sandra García Gallego
  • María de las Mercedes Alcón Calderón
  • Paula Ortega López
  • Héctor Elessar de Lucio Ortega
  • Antonio Jiménez Ruiz
  • Francisco Javier de la Mata de la Mata

COVID-19: un enfoque plural (p. 81-104) - 2021

Editor: Universidad de Alcalá

  • ISSN/ISBN 978-84-18254-36-9

This researcher has no conferences.

This researcher has no working papers.

This researcher has no technical reports.

This researcher has no research projects.

This researcher has no supervised thesis.

This researcher has no patents or software licenses.

Last data update: 9/16/23 4:16 PM