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Lucio Ortega, Héctor Elessar de

Química Orgánica y Química Inorgánica / Universidad de Alcalá

Publications

A functional BH3 domain in an aquaporin from Leishmania infantum

  • Genes, C.M.
  • de Lucio, H.
  • González, V.M.
  • Sánchez-Murcia, P.A.
  • Rico, E.
  • Gago, F.
  • Fasel, N.
  • Jiménez-Ruiz, A.
... View more Collapse

Cell Death Discovery - 2016

Editor: Springer Nature

10.1038/cddiscovery.2016.43 View at source

  • ISSN/ISBN 2058-7716

Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase

  • Sánchez-Murcia, P.A.
  • Ruiz-Santaquiteria, M.
  • Toro, M.A.
  • De Lucio, H.
  • Jiménez, M.Á.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Camarasa, M.-J.
  • Velázquez, S.
... View more Collapse

RSC Advances (p. 55784-55794) - 2015

Editor: Royal Society of Chemistry

10.1039/c5ra06853c View at source

  • ISSN/ISBN 2046-2069

Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles

  • Revuelto, A.
  • De Lucio, H.
  • García-Soriano, J.C.
  • Sánchez-Murcia, P.A.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Camarasa, M.-J.
  • Velázquez, S.
... View more Collapse

Journal of Medicinal Chemistry (p. 6137-6160) - 2021

Editor: American Chemical Society

10.1021/acs.jmedchem.1c00206 View at source

  • ISSN/ISBN 1520-4804

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity#

  • Ruiz-Santaquiteria, M.
  • Sánchez-Murcia, P.A.
  • Toro, M.A.
  • de Lucio, H.
  • Gutiérrez, K.J.
  • de Castro, S.
  • Carneiro, F.A.C.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Camarasa, M.-J.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry (p. 49-59) - 2017

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2017.04.020 View at source

  • ISSN/ISBN 1768-3254

Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity

  • de Lucio, H.
  • Revuelto, A.
  • Carriles, A.A.
  • de Castro, S.
  • García-González, S.
  • García-Soriano, J.C.
  • Alcón-Calderón, M.
  • Sánchez-Murcia, P.A.
  • Hermoso, J.A.
  • Gago, F.
  • Camarasa, M.-J.
  • Jiménez-Ruiz, A.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry - 2022

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2022.114878 View at source

  • ISSN/ISBN 1768-3254

Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library

  • Alcón-Calderón, M.
  • de Lucio, H.
  • García-Soriano, J.C.
  • Revuelto, A.
  • de Castro, S.
  • López-Gutiérrez, C.
  • San-Félix, A.
  • Quesada, E.
  • Gago, F.
  • Camarasa, M.-J.
  • Jiménez-Ruiz, A.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry - 2022

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2022.114675 View at source

  • ISSN/ISBN 1768-3254

Identification of NEK3 and MOK as novel targets for lithium

  • Bravo, A.
  • de Lucio, H.
  • Sánchez-Murcia, P.A.
  • Jiménez-Ruiz, A.
  • Petrone, P.M.
  • Gago, F.
  • Cortés Cabrera, A.
... View more Collapse

Chemical Biology and Drug Design (p. 965-969) - 2019

Editor: Blackwell Publishing Ltd

10.1111/cbdd.13487 View at source

  • ISSN/ISBN 1747-0285

Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides

  • de Lucio, H.
  • Gamo, A.M.
  • Ruiz-Santaquiteria, M.
  • de Castro, S.
  • Sánchez-Murcia, P.A.
  • Toro, M.A.
  • Gutiérrez, K.J.
  • Gago, F.
  • Jiménez-Ruiz, A.
  • Camarasa, M.-J.
  • Velázquez, S.
... View more Collapse

European Journal of Medicinal Chemistry (p. 615-623) - 2017

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2017.09.032 View at source

  • ISSN/ISBN 1768-3254

Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania

  • Genes, C.M.
  • de Lucio, H.
  • Sánchez-Murcia, P.A.
  • Gago, F.
  • Jiménez-Ruiz, A.

Cell Death and Disease - 2016

Editor: Nature Publishing Group

10.1038/cddis.2016.229 View at source

  • ISSN/ISBN 2041-4889

Pseudoirreversible slow-binding inhibition of trypanothione reductase by a protein–protein interaction disruptor

  • de Lucio, H.
  • Toro, M.A.
  • Camarasa, M.-J.
  • Velázquez, S.
  • Gago, F.
  • Jiménez-Ruiz, A.

British Journal of Pharmacology (p. 5163-5176) - 2020

Editor: John Wiley and Sons Inc

10.1111/bph.15250 View at source

  • ISSN/ISBN 1476-5381

This researcher has no books.

Investigación en nuevos fármacos frente a COVID-19

  • Sandra García Gallego
  • María de las Mercedes Alcón Calderón
  • Paula Ortega López
  • Héctor Elessar de Lucio Ortega
  • Antonio Jiménez Ruiz
  • Francisco Javier de la Mata de la Mata

COVID-19: un enfoque plural (p. 81-104) - 2021

Editor: Universidad de Alcalá

  • ISSN/ISBN 978-84-18254-36-9

This researcher has no conferences.

This researcher has no working papers.

This researcher has no technical reports.

This researcher has no research projects.

This researcher has no supervised thesis.

This researcher has no patents or software licenses.

Last data update: 9/16/23 4:16 PM