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Bautista Aguilera, Óscar Mauricio

Química Orgánica y Química Inorgánica / Universidad de Alcalá

Publications

Acetylcholinesterase inhibition of diversely functionalized quinolinones for alzheimer’s disease therapy

  • Bautista-Aguilera, Ó.M.
  • Ismaili, L.
  • Chioua, M.
  • Andrys, R.
  • Schmidt, M.
  • Bzonek, P.
  • Martínez-Grau, M.Á.
  • Beadle, C.D.
  • Vetman, T.
  • López-Muñoz, F.
  • Iriepa, I.
  • Refouvelet, B.
  • Musilek, K.
  • Marco-Contelles, J.
... View more Collapse

International Journal of Molecular Sciences (p. 1-20) - 2020

Editor: MDPI AG

10.3390/ijms21113913 View at source

  • ISSN/ISBN 1422-0067

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

  • Wang, L.
  • Esteban, G.
  • Ojima, M.
  • Bautista-Aguilera, O.M.
  • Inokuchi, T.
  • Moraleda, I.
  • Iriepa, I.
  • Samadi, A.
  • Youdim, M.B.H.
  • Romero, A.
  • Soriano, E.
  • Herrero, R.
  • Fernández Fernández, A.P.
  • Ricardo-Martínez-Murillo, null
  • Marco-Contelles, J.
  • Unzeta, M.
... View more Collapse

European Journal of Medicinal Chemistry (p. 543-561) - 2014

Editor: Elsevier Masson s.r.l.

10.1016/j.ejmech.2014.04.078 View at source

  • ISSN/ISBN 1768-3254

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

  • Bautista-Aguilera, O.M.
  • Esteban, G.
  • Bolea, I.
  • Nikolic, K.
  • Agbaba, D.
  • Moraleda, I.
  • Iriepa, I.
  • Samadi, A.
  • Soriano, E.
  • Unzeta, M.
  • Marco-Contelles, J.
... View more Collapse

European Journal of Medicinal Chemistry (p. 82-95) - 2014

10.1016/j.ejmech.2013.12.028 View at source

  • ISSN/ISBN 0223-5234

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids

  • Bautista-Aguilera, O.M.
  • Esteban, G.
  • Chioua, M.
  • Nikolic, K.
  • Agbaba, D.
  • Moraleda, I.
  • Iriepa, I.
  • Soriano, E.
  • Samadi, A.
  • Unzeta, M.
  • Marco-Contelles, J.
... View more Collapse

Drug Design, Development and Therapy (p. 1893-1910) - 2014

Editor: Dove Medical Press Ltd.

10.2147/dddt.s69258 View at source

  • ISSN/ISBN 1177-8881

Automated Synthesis of New Quinoxalinetacrines

  • Bautista-Aguilera, Ó.M.
  • Ismaili, L.
  • Chioua, M.
  • Iriepa, I.
  • Ángeles Martinez-Grau, M.
  • Beadle, C.D.
  • Vetman, T.
  • López-Muñoz, F.
  • Marco-Contelles, J.
... View more Collapse

ChemistrySelect (p. 6491-6493) - 2020

Editor: Wiley-Blackwell

10.1002/slct.202001593 View at source

  • ISSN/ISBN 2365-6549

Design, Synthesis and Biological Evaluation of Potent Antioxidant 1-(2,5-Dimethoxybenzyl)-4-arylpiperazines and N-Azolyl Substituted 2-(4-Arylpiperazin-1-yl)

  • Saadeh, H.A.
  • Khasawneh, M.A.
  • Samadi, A.
  • El-Haty, I.A.
  • Satała, G.
  • Bojarski, A.J.
  • Ismaili, L.
  • Bautista-Aguilera, Ó.M.
  • Yañez, M.
  • Mestres, J.
  • Marco-Contelles, J.
... View more Collapse

ChemistrySelect (p. 3854-3859) - 2017

Editor: Wiley-Blackwell

10.1002/slct.201700397 View at source

  • ISSN/ISBN 2365-6549

Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments

  • Bautista-Aguilera, Ó.M.
  • Ismaili, L.
  • Iriepa, I.
  • Diez-Iriepa, D.
  • Chabchoub, F.
  • Marco-Contelles, J.
  • Pérez, M.
... View more Collapse

Chemical Record (p. 162-174) - 2021

Editor: John Wiley and Sons Inc

10.1002/tcr.202000107 View at source

  • ISSN/ISBN 1528-0691

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1−42Aggregation Inhibitors for Alzheimer's Disease Therapy

  • Dgachi, Y.
  • Ismaili, L.
  • Knez, D.
  • Benchekroun, M.
  • Martin, H.
  • Szałaj, N.
  • Wehle, S.
  • Bautista-Aguilera, O.M.
  • Luzet, V.
  • Bonnet, A.
  • Malawska, B.
  • Gobec, S.
  • Chioua, M.
  • Decker, M.
  • Chabchoub, F.
  • Marco-Contelles, J.
... View more Collapse

ChemMedChem (p. 1318-1327) - 2016

Editor: John Wiley and Sons Ltd

10.1002/cmdc.201500539 View at source

  • ISSN/ISBN 1860-7187

Synthesis of N-Substituted Pyrroles Catalyzed by Low-Cost and Commercially Available Aluminas

  • Portilla-Zúñiga, O.
  • Bautista-Aguilera, Ó.M.
  • Martínez, J.J.
  • Rojas, H.
  • Macías, M.A.
  • Iriepa, I.
  • Pérez-Redondo, A.
  • Sathicq, Á.
  • Castillo, J.-C.
  • Romanelli, G.P.
... View more Collapse

Catalysts - 2023

Editor: MDPI

10.3390/catal13030603 View at source

  • ISSN/ISBN 2073-4344

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

  • Bautista-Aguilera, Ó.M.
  • Hagenow, S.
  • Palomino-Antolin, A.
  • Farré-Alins, V.
  • Ismaili, L.
  • Joffrin, P.-L.
  • Jimeno, M.L.
  • Soukup, O.
  • Janočková, J.
  • Kalinowsky, L.
  • Proschak, E.
  • Iriepa, I.
  • Moraleda, I.
  • Schwed, J.S.
  • Romero Martínez, A.
  • López-Muñoz, F.
  • Chioua, M.
  • Egea, J.
  • Ramsay, R.R.
  • Marco-Contelles, J.
  • Stark, H.
... View more Collapse

Angewandte Chemie - International Edition (p. 12765-12769) - 2017

Editor: Wiley-VCH Verlag

10.1002/anie.201706072 View at source

  • ISSN/ISBN 1521-3773

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This researcher has no supervised thesis.

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Last data update: 4/24/24 1:00 PM