The data shown for the Universidad Carlos III de Madrid are partial, as they are intended to answer 2 questions:

  • Who is researching a specific topic?
  • What is an expert, group or particular department researching?

The search results will adhere to the following limits: active Researchers at Carlos III University of Madrid, Projects since 2006 and Publications, Theses, Patents and Software since 2008.

Larcher Laguzzi, Fernando flarcher@ing.uc3m.es

Publications

Long-term skin regeneration from a gene-targeted human epidermal stem cell clone

  • Duarte Gonzalez, Blanca
  • Miselli, Francesca
  • Murillas Angoiti, Rodolfo
  • Espinosa Hevia, Luis
  • Cruz Cigudosa, Juan
  • Recchia, Alessandra
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
... View more Collapse

MOLECULAR THERAPY (p. 1878-1880) - 11/2014

https://doi.org/10.1038/mt.2014.187 View at source

  • EISSN 1525-0024
  • ISSN 1525-0016
Open Access

Long-Term faithful recapitulation of transglutaminase 1-deficient lamellar ichthyosis in a skin-humanized mouse model, and insights from proteomic studies

  • Aufenvenne, Karin
  • Rice, Robert H.
  • Hausse, Ingrid
  • Oji, Vinzenz
  • Hennies, Hans Crhristian
  • Rio Nechaevsky, Marcela Andrea Del
  • Traupe, Heiko
  • Larcher Laguzzi, Fernando
... View more Collapse

JOURNAL OF INVESTIGATIVE DERMATOLOGY (p. 1918-1921) - 7/2012

https://doi.org/10.1038/jid.2012.65 View at source

  • EISSN 1523-1747
  • ISSN 0022-202X

Keratinocyte cell lines derived from severe generalized recessive Epidermolysis Bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo

  • Chamorro, Cristina
  • Almarza, David
  • Duarte Gonzalez, Blanca
  • Gonzalez Llames, Sara
  • Murillas Angoiti, Rodolfo
  • Garcia Diez, Marta
  • Cigudosa, Juan C.
  • Espinosa Hevia, Luis
  • Escamez Toledano, Maria Jose
  • Mencia Rodriguez, Angeles
  • Meana Infiesta, Alvaro Enrique
  • Garcia-escudero, Ramon
  • Moro, Rosa
  • Conti, Claudio Jorge
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
... View more Collapse

EXPERIMENTAL DERMATOLOGY (p. 601-603) - 9/2013

https://doi.org/10.1111/exd.12203 View at source

  • EISSN 1600-0625
  • ISSN 0906-6705

Innovative therapeutic strategies for recessive dystrophic epidermolysis bullosInnovative therapeutic strategies for recessive dystrophic epidermolysis bullosa

  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del

Actas dermo-sifilográficas (English edition) (p. 376-382) - 5/2015

https://doi.org/10.1016/j.ad.2015.01.007 View at source

  • EISSN 1578-2190
  • ISSN 0001-7310

Induction of<br/>scleroderma fibrosis in skin-humanized mice by anti-Platelet-Derived Growth<br/>Factor receptor agonistic autoantibodies

  • Luchetti, M.m.
  • Moroncini, G.
  • Escamez Toledano, Maria Jose
  • Svegliati Baroni, S.
  • Spadoni, T.
  • Grieco, A.
  • Paolini, C.
  • Funaro, A.
  • Avvedimento, E.v.
  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del
  • Gabrielli, A.
... View more Collapse

Arthritis & Rheumatology (p. 2263-2273) - 8/2016

https://doi.org/10.1002/art.39728 View at source

  • EISSN 2326-5205
  • ISSN 2326-5191
Open Access

In-vivo, non-invasive detection of hyperglycemic states in animal models using mm-wave spectroscopy

  • Martin Mateos, Pedro
  • Dornuf, Fabian
  • Duarte Gonzalez, Blanca
  • Hils, Bernhard
  • Moreno Oyervides, Aldo Luis
  • Bonilla Manrique, Oscar Elias
  • Larcher Laguzzi, Fernando
  • Krozer, Viktor
  • Acedo Gallardo, Pablo
... View more Collapse

Scientific Reports (p. 1-8) - 9/2016

https://doi.org/10.1038/srep34035 View at source

  • ISSN 2045-2322
Open Access

In vivo assessment of acute UVB responses in normal and xeroderma pigmentosum (XP-C) skin-humanized mouse models

  • Garcia Diez, Marta
  • Llames, Sara
  • García, Eva
  • Meana Infiesta, Alvaro Enrique
  • Cuadrado-corrales, Natividad
  • Recasens, Mar
  • Puig, Susana
  • Nagore, Eduardo
  • Illera Esteban, Nuria
  • Jorcano Noval, Jose Luis
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
... View more Collapse

AMERICAN JOURNAL OF PATHOLOGY (p. 865-872) - 8/2010

https://doi.org/10.2353/ajpath.2010.091096 View at source

  • ISSN 0002-9440

In vitro and in vivo wound healing-promoting activities of human cathelicidin LL-37

  • Carretero Trillo, Marta
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Duarte Gonzalez, Blanca
  • Holguin Fernandez, Almudena
  • Luisa, Retamosa
  • Jorcano Noval, Jose Luis
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
... View more Collapse

BRITISH JOURNAL OF DERMATOLOGY (p. 223-236) - 1/2008

https://doi.org/10.1038/sj.jid.5701043 View at source

  • EISSN 1365-2133
  • ISSN 0007-0963
Open Access

Humanization of tumor stroma by tissue engineering as a tool to improve squamous cell carcinoma xenograft

  • Guerrero Aspizua, Sara
  • González Masa, Andrea
  • Conti, Claudio Jorge
  • Garcia Diez, Marta
  • Chacon Solano, Esteban Gonzalo
  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del
... View more Collapse

International Journal of Molecular Sciences (p. 1-10) - 1/2020

https://doi.org/10.3390/ijms21061951 View at source

  • EISSN 1422-0067
  • ISSN 1661-6596
Open Access

Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression

  • Di, Wei-li
  • Semenova, Ekaterina
  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del
  • Harper, John I.
  • Thrasher, Adrian J.
  • Qasim, Waseem
... View more Collapse

HUMAN GENE THERAPY (p. 83-90) - 1/2012

https://doi.org/10.1089/hum.2011.091 View at source

  • EISSN 1557-7422
  • ISSN 1043-0342

This researcher has no books.

Open Access

Organotypic and humanized animal models of genodermatoses. In: Skin tissue models

  • Chacon Solano, Esteban Gonzalo
  • Guerrero Aspizua, Sara
  • Martinez Santamaria, Lucia
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando

Skin tissue models (p. 77-102) - 11/2017

Editor: Academic Press

https://doi.org/10.1016/c2016-0-00093-1 View at source

  • ISBN 978-0-12-810545-0

Current applications for bioengineered skin. In: Translating regenerative medicine to the clinic. Advances in translational medicine

  • Guerrero Aspizua, Sara
  • Conti, Claudio Jorge
  • Zapatero Solana, Elisabet
  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del

Translating regenerative medicine to the clinic. Advances in translational medicine (p. 107-120) - 12/2016

Editor: Academic Press

10.1016/b978-0-12-800548-4.00008-5 View at source

Bioengineered Skin. In: Skin Biopsy: Perspectives

  • Escamez Toledano, Maria Jose
  • Martinez Santamaria, Lucia
  • Garcia Diez, Marta
  • Guerrero Aspizua, Sara
  • Carretero Trillo, Marta
  • Larcher Laguzzi, Fernando
  • Meana Infiesta, Alvaro Enrique
  • Rio Nechaevsky, Marcela Andrea Del
... View more Collapse

Skin Biopsy: Perspectives (p. 261-296) - 11/2011

Editor: INTECH

https://doi.org/10.5772/23587 View at source

  • ISBN 978-953-307-290-6

Topical enzyme replacement therapy restores transglutaminase 1 activity and corrects architecture of transglutaminase 1 deficient skin grafts

  • Aufenvenne, K.
  • Larcher Laguzzi, Fernando
  • Hausser, Ingrid
  • Rio Nechaevsky, Marcela Andrea Del
  • Dathe, M.
  • Traupe, H.

42nd Annual Meeting of the European Society for Dermatological Research (ESDR 2012) (p. 89-89) - 2012

https://doi.org/10.1038/jid.2012.304 View at source

  • ISBN 0022-202X

Targeted Gene Therapy Approaches for RDEB Due to a Highly Recurrent COL7A1 "Spanish" Mutation

  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del

DEBRA International Triennial Research Symposium - 2015

Síndrome de Netherton: de los modelos animales, al paciente. Ensayo clínico de terapia génica, para Síndrome de Netherton

  • Larcher Laguzzi, Fernando

XIV Jornadas de Convivencia de Afectados de Ictiosis - 2016

Safety criteria and patient selection in a cell-based clinical trial for the systemic treatment of recessive dystrophic epidermolysis bullosa: MesenSistem-EB

  • Bonafont Arago, Jose
  • Mencia Rodriguez, Angeles
  • Srifa, W.
  • Vaidyanathan, S.
  • Romano, R.
  • Garcia, M
  • Escamez, M.j.
  • Duarte Gonzalez, Blanca
  • Porteus, M.h.
  • Del Rio, M.
  • Murillas Angoiti, Rodolfo
  • Larcher Laguzzi, Fernando
... View more Collapse

ESGCT 27th Annual Congress In collaboration with SETGyc - 2019

https://doi.org/10.1089/hum.2019.29095.abstracts View at source

Role of mitochondria in the pathogenesis of kindler syndrome

  • García, S.c. (crespo García)
  • Malik, G.r.
  • Moro Muñoz, Rosa Maria
  • Rio Nechaevsky, Marcela Andrea Del
  • Jorcano Noval, Jose Luis
  • Larcher Laguzzi, Fernando

The European Society for Gene and Cell Therapy and the Spanish Society for Gene and Cell Therapy Collaborative Congress ((ESGCT and SETGyC Collaborative Congress) (p. 130-130) - 2013

Editor: Mary Anne Liebert

https://doi.org/10.1089/hum.2013.2513 View at source

  • ISBN 1043-0342
Open Access

Preliminary safety and efficacy outcomes of a phase I trial of systemic mesenchymal stromal cells for recessive dystrophic epidermolysis bullosa

  • Martinez Santamaria, Lucia
  • Chacon Solano, Esteban Gonzalo
  • Garcia Diez, Marta
  • Escamez Toledano, Maria Jose
  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del
  • Masseda, R.
  • Sacedon, R.
  • De Arriba, M.c.
  • Jimenez, E.
  • Garcia Sevilla, Monica
  • Chacon, E.
  • Suarez Sancho, S.
  • Fernandez Bello, I.
  • Carretero, M.
  • Yañez, R.
  • Lwin, S.m.
  • Martinez Queipo, M.
  • Liu, L.
  • Mee, J.
  • De Paz, R.
  • Borobia, A.
  • Fernandez Santos, M.e.
  • Butta, N.
  • Yuste, V.
  • Macgrath, J.a.
  • Del Rio, M.
  • Vice, A.
  • De Lucas, R.
  • Escamez, M.j.
... View more Collapse

EB2020 1st World Congress on Epidermolysis Bullosa (p. 57-57) - 2020

  • ISBN 0001-5555

Potential role of oxidative stress from mitochondria in Kindler Syndrome

  • Chamorro, C.
  • Almarza, D.
  • Llames, Sara
  • Murillas Angoiti, Rodolfo
  • Cigudosa, J.
  • Escamez Toledano, Maria Jose
  • Mencia Rodriguez, Angeles
  • Garcia-escudero, R.
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
... View more Collapse

42nd Annual Meeting of the European Society for Dermatological Research (ESDR 2012) (p. 82-82) - 2012

https://doi.org/10.1038/jid.2012.302 View at source

  • ISBN 0022-202X
Open Access

Novel players in the establishment and progression of fibrosis in recessive dystrophic epidermolysis bullosa

  • Chacon Solano, Esteban Gonzalo
  • Quero, Francisco
  • Garcia Diez, Marta
  • Escamez Toledano, Maria Jose
  • Nystrom, Alexander
  • Larcher Laguzzi, Fernando
  • Rio Nechaevsky, Marcela Andrea Del
... View more Collapse

EB2020 1st World Congress on Epidermolysis Bullosa (p. 71-71) - 2020

  • ISBN 0001-5555

Novedades en el tratamiento de la Epidermolisis Bullosa distrófica /Advances in DEB treatment

  • Larcher Laguzzi, Fernando

International symposium Rare skin diseases: from clinic to gene and vice versa - 2016

Non-invasive Detection and Monitoring of Sustained Glycemic Fluctuations using Mm-Wave Spectroscopy

  • Moreno-overvides, A.
  • Martin Mateos, Pedro
  • Aguilera Morillo, Maria Del Carmen
  • Ulisse, G.
  • Larcher Laguzzi, Fernando
  • Krozer, V.
  • Acedo Gallardo, Pablo
... View more Collapse

EuMC 2018. 48th European Microwave Conference - 2018

Editor: IEEE.THE INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS, INC

https://doi.org/10.23919/eumc.2018.8541413 View at source

  • ISBN 978-2-87487-051-4

This researcher has no working papers.

This researcher has no technical reports.

Test study with humanized mice to determine glucose values using a new glucometer

  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando

Period: 29-01-2018 - 08-02-2018

Type of funding: European

Funding entity: DIAMON TECH GMBH

Terapias Avanzadas en piel:Investigación Traslacional

  • Rio Nechaevsky, Marcela Andrea Del
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Larcher Laguzzi, Fernando
  • Guerrero Aspizua, Sara
  • Martinez Santamaria, Lucia

Period: 01-01-2017 - 31-12-2017

Type of funding: Regional

Funding entity: INSTITUTO DE INVESTIGACION SANITARIA - FUNDACION JIMENEZ DIAZ

Pre-clinical development of a gene editing medicinal product for epidermolysis bullosa

  • Rio Nechaevsky, Marcela Andrea Del
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Larcher Laguzzi, Fernando
  • Martinez Santamaria, Lucia
  • Leon Canseco, Carlos
  • Bonafont Arago, Jose
  • Chacon Solano, Esteban Gonzalo
... View more Collapse

Period: 20-03-2020 - 15-06-2022

Type of funding: European

Funding entity: SOHANA RESEARCH FUND, CURE EB

662629 - NanoSmells: Artificial remote-controlled odorants

  • Rio Nechaevsky, Marcela Andrea Del
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Larcher Laguzzi, Fernando
  • Guerrero Aspizua, Sara
  • Martinez Santamaria, Lucia
  • Velasco Bayon, Diego
  • Leon Canseco, Carlos
  • Diaz Mayoral, Francisco Jose
  • Arriba Perez, Maria Del Carmen De
  • Pajuelo Lozano, Natalia
... View more Collapse

Period: 01-09-2015 - 30-09-2019

Type of funding: European

Funding entity: EUROPEAN COMMISSION RESEARCH EXECUTIVE AGENCY

Generación de líneas celulares modificadas genéticamente conteniendo mutaciones sin sentido representativas en genes causantes de enfermedades genéticas de piel (epidermilosis bullosa y otras) y uso de un modelo organotípico para identificación de compuestos inductores de traducción de lectura (TRIDs)

  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Murillas Angoiti, Rodolfo
  • Bonafont Arago, Jose
  • Chacon Solano, Esteban Gonzalo
  • Duarte Gonzalez, Blanca
... View more Collapse

Period: 17-07-2019 - 31-12-2021

Type of funding: National

Funding entity: ALMIRALL, S.A

EC-GA 261392 - GENEGRAFT: Phase I/II ex vivo gene therapy clinical trial for Recessive Dystrophic Epidermolysis Bullosa using skin equivalent grafts genetically corrected with a COL7A1-encoding SIN retroviral

  • Rio Nechaevsky, Marcela Andrea Del
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Larcher Laguzzi, Fernando
  • Guerrero Aspizua, Sara
  • Martinez Santamaria, Lucia
  • Garcia Perez, Eva
  • Mancinelli, Mariachiara
... View more Collapse

Period: 01-03-2014 - 31-12-2017

Type of funding: European

Funding entity: EUROPEAN COMMISSION RESEARCH EXECUTIVE AGENCY

Larcher 1 Debra Grant - Designer nucleases-based NHEJ-mediated gene editing for the correction of a highly recurrent COL7A1 mutation in recesive dystrophic epidermolysis bullosa epidermal stem cells

  • Larcher Laguzzi, Fernando
  • Chamorro Poyo, Cristina

Period: 20-02-2017 - 19-02-2019

Type of funding: European

Funding entity: DEBRA AUSTRIA

DTS17/00135 - Desarrollo, validación y evaluación de una nueva herramienta no invasiva para medir la hiperglucemia sostenida usando espectroscopia de ondas milimétricas

  • Acedo Gallardo, Pablo
  • Durban Reguera, Maria Luz
  • Ruiz Llata, Marta
  • Martin Mateos, Pedro
  • Jorcano Noval, Jose Luis
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
  • Martinez Santamaria, Lucia
  • Aguilera Morillo, Maria Del Carmen
  • De La Cruz Fernandez, Maria Jose
  • Llanos Jimenez, Lucia
  • Lecumberri Pascual, Edurne
... View more Collapse

Period: 01-01-2018 - 31-12-2019

Type of funding: National

Funding entity: INSTITUTO DE SALUD CARLOS III

DTS19/00146 - Desarrollo, validación y evaluación de un nuevo sistema de monitorización no invasiva de colgajos (flaps) en cirugía reconstructiva

  • Martin Mateos, Pedro
  • Acedo Gallardo, Pablo
  • Jorcano Noval, Jose Luis
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando
  • Martinez Mendez, Jose Ramon
  • Largo Aramburu, Carlota
  • Diaz Ojeda, Luis
... View more Collapse

Period: 01-01-2020 - 31-10-2022

Type of funding: National

Funding entity: INSTITUTO DE SALUD CARLOS III

Cátedra de Investigación Fundación Jiménez Díaz de medicina regenerativa y bioingeniería de tejidos

  • Rio Nechaevsky, Marcela Andrea Del
  • Martin Mateos, Pedro
  • Escamez Toledano, Maria Jose
  • Garcia Diez, Marta
  • Larcher Laguzzi, Fernando
  • Guerrero Aspizua, Sara
  • Martinez Santamaria, Lucia
  • Mencia Rodriguez, Angeles
  • Zapatero Solana, Elisabet
  • Conti, Claudio Jorge
  • Garcia Martin, Adela Maria
  • Moreno Oyervides, Aldo Luis
  • Velasco Bayon, Diego
  • Leon Canseco, Carlos
  • Bonafont Arago, Jose
  • Chacon Solano, Esteban Gonzalo
  • Arriba Perez, Maria Del Carmen De
  • Muñoz Mayoral, Evangelina
  • Lopez Manzaneda, Sergio
  • Herraiz Gil, Sara
... View more Collapse

Period: 01-06-2014 - 31-12-2022

Type of funding: Regional

Funding entity: INSTITUTO DE INVESTIGACION SANITARIA - FUNDACION JIMENEZ DIAZ

Identification and functional characterization of mutation-independent disease-severity modulators in recessive dystrophic epidermolysis bullosa

  • Chacon Solano, Esteban Gonzalo
  • Ruiz Mezcua, Maria Belen
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando

Reading date: 18-03-2022

GENE EDITING-BASED PROTOCOLS FOR THE EX VIVO CORRECTION OF RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA

  • Bonafont Arago, Jose
  • Rio Nechaevsky, Marcela Andrea Del
  • Larcher Laguzzi, Fernando

Reading date: 28-09-2020

This researcher has no patents or software licenses.

Last data update: 2/7/24 8:44 AM