Specific Peptide from the Novel W-Tau Isoform Inhibits Tau and Amyloid ? Peptide Aggregation In Vitro - Cuadros R, Pérez M, Ruiz-Gabarre D, Hernández F, García-Escudero V, Avila J (Acs Chemical Neuroscience, 2022)

A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer?s disease - García-Escudero V; Ruiz-Gabarre D; Gargini R; Pérez M; García E; Cuadros R; Hernández IH; Cabrera JR; García-Escudero R; Lucas JJ; Hernández F; Ávila J (Acta Neuropathologica, 2021)

Protein biomarkers for the diagnosis of alzheimer?s disease at different stages of neurodegeneration - Pérez M; Hernández F; Avila J (International Journal Of Molecular Sciences, 2020)

Role of tau N-terminal motif in the secretion of human tau by End Binding proteins. - Sayas CL, Medina M, Cuadros R, Ollá I, García E, Pérez M, Ferrer I, Hernández F, Avila J (Plos One, 2019)

Propagation of Tau via Extracellular Vesicles - Perez, Mar; Avila, Jesus; Hernandez, Felix; (Frontiers In Neuroscience, 2019)

Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment - Ritter, Maxi L.; Avila, Jesus; Garcia-Escudero, Vega; Hernandez, Felix; Perez, Mar; (Frontiers In Cellular Neuroscience, 2018)

Secretion of full-length Tau or Tau fragments in cell culture models. Propagation of Tau in vivo and in vitro. - Pérez M, Medina M, Hernández F, Avila J (Biomolecular Concepts, 2018)

New Beginnings in Alzheimer's Disease: The Most Prevalent Tauopathy - Hernandez, Felix; Llorens-Martin, Maria; Bolos, Marta; Perez, Mar; Cuadros, Raquel; Pallas-Bazarra, Noemi; Zabala, Juan C.; Avila, Jesus; (Journal Of Alzheimers Disease, 2018)

Secretion of full-length tau or tau fragments in a cell culture model - Pérez M, Cuadros R, Hernández F, Avila J (Neuroscience Letters, 2016)

Estudio del papel de la proteína TAU en la modulación de la neurogénesis hipocampal adulta - Perez Martinez, Maria Mar (Autor o Coautor); Correas Hornero, Maria Isabel (Autor o Coautor); Noemí Pallas?Bazarra (Director); Hernandez Perez, Felix (Autor o Coautor) Doctorando: Noemí Pallas?Bazarra (2015)

Boronate-Tau Mediated Uptake in Neurons - Pérez M, Cuadros R, Pallas-Bazarra N, García C, Langa E, Jurado-Arjona J, Hernández F, Avila J (Journal Of Alzheimers Disease, 2014)

La patología de granos argirófilos y la taupatía de tipo Alzheimer: características comunes y diferenciales - Perez Martinez, Maria Mar (Autor o Coautor); Bullido Gomez-Heras, Maria Jesus (Autor o Coautor); Ávila de Grado, Jesús (Director) (2014)

Regulación de la expresión de Mad2L1 por microRNAs y su correlación con la respuesta a terapia en Cáncer Gástrico: biomarcadores predictivos de respuesta - Perez Martinez, Maria Mar (Investigador/a); Cales Bourdet, Maria del Carmen (Investigador/a); Sanchez Perez, Maria Isabel (Investigador principal (IP)) (2013)

Differential survival and sensitivity of neural precursors during development and the role of the dna damage response and glucocorticoids in the cell survival mechanisms of both neural stem and astrocytoma cells, compared to an alzheimer¿s model - Perez Martinez, Maria Mar (Autor o Coautor); Avendaño Trueba, Carlos (Autor o Coautor); Nuñez Molina, Angel (Autor o Coautor); Nuñez Molina, Angel (Tutor) (2013)

GSK3? overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus - Sirerol-Piquer MS; Gomez-Ramos P; Hernández F; Perez M; Morán MA; Fuster-Matanzo A; Lucas JJ; Avila J; García-Verdugo JM (Hippocampus, 2011)

Tau Kinase I Overexpression Induces Dentate Gyrus Degeneration - Avila J, Gómez de Barreda E, Engel T, Pérez M, Martín-Maestro P, Fuster-Matanzo A, Goñi-Oliver P, Lucas JJ, Hernández F (Neurodegenerative Diseases, 2010)

Tau-knockout mice show reduced GSK3-induced hippocampal degeneration andlearning deficits - Gómez de Barreda E, Pérez M, Gómez Ramos P, de Cristobal J, Martín-Maestro P, Morán A, Dawson HN, Vitek MP, Lucas JJ, Hernández F, Avila J (Neurobiology Of Disease, 2010)

Role of clathrin in the inmune synapse formation - Calabia-Linares C; Alfonso-Pérez M; Martín-Cofreces N; Pérez-Martínez M; Aguado-Ballano C; Urbano-Olmos F; Sánchez-Sorzano C; Sánchez-Madrid F; Veiga E (Microscopy And Microanalysis, 2009)

Tau - An inhibitor of deacetylase HDAC6 function - Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J (Journal Of Neurochemistry, 2009)

Binding of hsp90 to tau promotes a conformational change and aggregation of tau protein - Tortosa E; Santa-Maria I; Moreno F; Lim F; Perez M; Avila J (Journal Of Alzheimers Disease, 2009)

Tau as a molecular marker of development, aging and neurodegenerative disorders - Hernandez Perez, Felix; Perez Martinez, Maria Mar (Current Aging Science, 2008)

The role of the VQIVYK peptide in tau protein phosphorylation - Hernandez Perez, Felix; Perez Martinez, Maria Mar; Perez, Mar; Santa-Maria, Ismael; Tortosa, Elena; Cuadros, Raquel; del Valle, Mercedes; Hernandez, Felix; Moreno, Francisco J; Avila, Jesus (Journal Of Neurochemistry, 2007)

Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1? - Rey M; Valenzuela-Fernández A; Urzainqui A; Yáñez-Mó M; Pérez-Martínez M; Penela P; Mayor F; Sánchez-Madrid F (Journal Of Cell Science, 2007)

In vitro tau fibrillization: Mapping protein regions - Santa-María I; Pérez M; Hernández F; Muñoz V; Moreno FJ; Avila J (Biochimica Et Biophysica Acta-Molecular Basis Of Disease, 2006)

Tau phosphorylation, aggregation, and cell toxicity - Avila J; Santa-María I; Pérez M; Hernández F; Moreno F (Journal Of Biomedicine And Biotechnology, 2006)

Characteristics of the binding of thioflavin S to tau paired helical filaments - Santa-María I; Pérez M; Hernández F; Avila J; Moreno FJ (Journal Of Alzheimers Disease, 2006)

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice - Lim, Filip; Perez Martinez, Maria Mar; Moran Cabre, Maria Asuncion; Gomez Ramos, Pilar; Ribe, EM; Perez, M; Puig, B; Gich, I; Cuadrado, M; Sesma, T; Catena, S; Sanchez, B; et al. (Neurobiology Of Disease, 2005)

Characterization of Alzheimer paired helical filaments by electron microscopy - Hernández F, Engel T, Gómez-Ramos A, Pérez M, Avila J (Microscopy Research And Technique, 2005)

Characterization of a double (amyloid precursor protein-tau) transgenic: Tau phosphorylation and aggregation - Pérez M; Ribe E; Rubio A; Lim F; Morán MA; Ramos PG; Ferrer I; Isla MTG; Avila J (Neuroscience, 2005)

Tau in neurodegenerative diseases: Tau phosphorylation and assembly - Avila, J; Pérez, M; Lim, F; Gómez-Ramos, A; Hernández, F; Lucas, JJ; (Neurotoxicity Research, 2004)

Role of Tau Protein in Both Physiological and Pathological Conditions - Avila J, Lucas JJ, Perez M, Hernandez F (Physiological Reviews, 2004)

Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicingand intranuclear distribution of SC35 - Implications for Alzheimer'sdisease - Hernández F, Pérez M, Lucas JJ, Mata AM, Bhat R, Avila J (Journal Of Biological Chemistry, 2004)

Interaction of Alzheimer's disease amyloid ? peptide fragment 25-35 with tau protein, and with a tau peptide containing the microtubule binding domain - Perez, M; Cuadros, R; Benitez, MJ; Jimenez, JS; (Journal Of Alzheimers Disease, 2004)

Assembly in vitro of tau protein and its implications in Alzheimer's disease. - Avila J; Pérez M; Lucas JJ; Gómez-Ramos A; Santa María I; Moreno F; Smith M; Perry G; Hernández F (Current Alzheimer Research, 2004)

Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3 - Perez, M; Rojo, AI; Wandosell, F; Diaz-Nido, J; Avila, J; (Biochemical Journal, 2003)

Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model - Pérez M., Hernández F., Lim F., Díaz-Nido J., Avila J. (Journal Of Alzheimers Disease, 2003)

Alpha-helix structure in Alzheimer's disease aggregates of tau-protein - Sadqi M, Hernández F, Pan U, Pérez M, Schaeberle MD, Avila J, Muñoz V (Biochemistry, 2002)

Sulfo-glycosaminoglycan content affects PHF-tau solubility and allows the identification of different types of PHFs - Hernández F, Pérez M, Lucas JJ, Avila J (Brain Research, 2002)

Formation of aberrant phosphotau fibrillar polymers in neural cultured cells - Pérez M, Hernández F, Gómez-Ramos A, Smith M, Perry G, Avila J (European Journal Of Biochemistry, 2002)

The FTDP-17-linked mutation R406W abolishes the interaction ofphosphorylated tau with microtubules - Pérez M, Lim F, Arrasate M, Avila J (Journal Of Neurochemistry, 2000)

Tau aggregation - Hernández F, Ferrer I, Pérez M, Zabala JC, Del Rio JA, Avila J (Neuroscience, 2023)

Alteraciones mitocondriales y de los mecanismos autofágicos en modelos experimentales de la enfermedad de Alzheimer - Carro Díaz, Eva María (Director); Bartolomé Robledo, Fernando (Director); Perez Martinez, Maria Mar (Tutor) Doctorando: Cueva de Vicente, Macarena de la (2021)

Tau assembly into filaments - Pérez M; Cuadros R; Medina M (Methods In Molecular Biology, 2018)

Cathepsin D in a murine model of frontotemporal dementia with parkinsonism-linked to chromosome 17 - Fernández-Montoya J; Pérez M (Journal Of Alzheimers Disease, 2015)

Longitudinal Assessment of a Transgenic Animal Model of Tauopathy by FDG-PET Imaging - de Cristóbal J, García-García L, Delgado M, Pérez M, Pozo MA, Medina M (Journal Of Alzheimers Disease, 2014)

Ultrastructural localization of fructose-1,6-bisphosphatase in mouse brain - Velásquez ZD; Pérez M; Morán MA; Yanez AJ; Ávila J; Slebe JC; Gómez-ramos P (Microscopy Research And Technique, 2011)

A novel GSK-3 beta inhibitor reduces Alzheimer's pathology and rescuesneuronal loss in vivo - Serenó L, Coma M, Rodríguez M, Sánchez-Ferrer P, Sánchez MB, Gich I, Agulló JM, Pérez M, Avila J, Guardia-Laguarta C, Clarimón J, Lleó A, Gómez-Isla T (Neurobiology Of Disease, 2009)

Altered Ca2+ dependence of synaptosomal plasma membrane Ca2+-ATPase inhuman brain affected by Alzheimer's disease - Berrocal M, Marcos D, Sepúlveda MR, Pérez M, Avila J, Mata AM (Faseb Journal, 2009)

Estudio de alteraciones lisosomales, y su relación con la proteína tau, en cerebros humanos y en un modelo transgénico de la enfermedad de alzherimer. - Gomez Ramos, Pilar (Investigador/a); Moran Cabre, Maria Asuncion (Investigador/a); Perez Martinez, Maria Mar (Investigador principal (IP)) (2009)

Effect of cortistatin on tau phosphorylation at Ser262 site - Rubio A, Pérez M, de Lecea L, Avila J (Journal Of Neuroscience Research, 2008)

Phosphorylated tau in neuritic plaques of APPsw/ Tauvlw transgenic mice and Alzheimer disease - Pérez M; Morán MA; Ferrer I; Ávila J; Gómez-Ramos P (Acta Neuropathologica, 2008)

Microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of microtubule tyrosination - Utreras, Elias; Jimenez-Mateos, Eva Maria; Contreras-Vallejos, Erick; Tortosa, Elena; Perez, Mar; Rojas, Sebastian; Saragoni, Lorena; Maccioni, Ricardo B.; Avila, Jesus; Gonzalez-Billault, Christian; (Developmental Neuroscience, 2007)

Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease - Perez Martinez, Maria Mar; Muntane, G; Dalfo, E; Martinez, A; Rey, M J; Avila, J; Perez, M; Portero, M; Pamplona, R; Ayala, V; Ferrer, I (Journal Of Neurochemistry, 2006)

Effect of acetylcholine on tau phosphorylation in human neuroblastoma cells - Rubio A, Avila J, Pérez M (Journal Of Molecular Neuroscience, 2006)

Acetylcholine receptors and tau phosphorylation - Rubio A, Pérez M, Avila J (Current Molecular Medicine, 2006)

?-Cleavage-Independent Functions of Presenilin, Nicastrin, and Aph-1 Regulate Cell-Junction Organization and Prevent Tau Toxicity In Vivo - Doglio LE, Kanwar R, Jackson GR, Perez M, Avila J, Dingwall C, Dotti CG, Fortini ME, Feiguin F (Neuron, 2006)

Acetylsalicylic acid decreases tau phosphorylation at serine 422 - Tortosa, E; Avila, J; Perez, M; (Neuroscience Letters, 2006)

A new mutation of the tau gene, G303V, in early-onset familial progressive supranuclear palsy - Ros R, Thobois S, Streichenberger N, Kopp N, Sánchez MP, Pérez M, Hoenicka J, Avila J, Honnorat J, de Yébenes JG (Archives Of Neurology, 2005)

Role for the ?-helix in aberrant protein aggregation - Kunjithapatham R, Oliva FY, Doshi U, Pérez M, Avila J, Muñoz V (Biochemistry, 2005)

Análisis de la polimerización de la proteina asociada a microtúbulos tau en diferentes tauopatías. - Alicia Rubio Garrido (Investigador/a); Alberto Gomez Ramos (Investigador/a); Perez Martinez, Maria Mar (Investigador/a); Grado Jesus Avila DE (Investigador principal (IP)) (2005)

Estradiol prevents neural tau hyperphosphorylation characteristic of Alzheimer's disease - Alvarez-de-la-Rosa M, Silva I, Nilsen J, Pérez MM, García-Segura LM, Avila J, Naftolin F (Annals Of The New York Academy Of Sciences, 2005)

Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus - Cardona-Gomez P, Perez M, Avila J, Garcia-Segura LM, Wandosell F (Molecular And Cellular Neuroscience, 2004)

Characterization by Atomic Force Microscopy of Alzheimer Paired Helical Filaments under Physiological Conditions - Moreno-Herrero F; Pérez M; Baró AM; Avila J (Biophysical Journal, 2004)

Inhibition by Aplidine of the aggregation of the prion peptide PrP 106-126 into ?-sheet fibrils - Pérez M, Sadqi M, Muñoz V, Avila J (Biochimica Et Biophysica Acta. Molecular Basis Of Disease, 2003)

La proteína tau - Perez Martinez, Maria Mar (Alzheimer 2003 : ¿Qué Hay De Nuevo?, 2003)

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? - Perez Martinez, Maria Mar (Free Radical Biology And Medicine, 2002)

In vitro assembly of tau protein: Mapping the regions involved in filament formation - Pérez M, Arrasate M, Montejo De Garcini E, Muñoz V, Avila J (Biochemistry, 2001)

Oxidative Damage and Antioxidant Responses in Alzheimer's Disease - Perez Martinez, Maria Mar (Alzheimer's Disease: Advances In Etiology, Pathogenesis And Therapeutics, 2001)

Characterization by atomic force microscopy and cryoelectron microscopy of tau polymers assembled in Alzheimer's disease - Moreno-Herrero, Fernando; Valpuesta, Jose M.; Perez, Mar; Colchero, Jaime; Baro, Arturo M.; Avila, Jesus; Montejo de Garcini, Esteban; (Journal Of Alzheimers Disease, 2001)

Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal - Pérez M, Cuadros R, Smith MA, Perry G, Avila J (Febs Letters, 2000)

Tau dephosphorylation at Tau-1 site correlates with its association to cell membrane - Arrasate M, Pérez M, Avila J (Neurochemical Research, 2000)

Gsk3ß-mediated phosphorylation of the microtubule-associated protein 2C (MAP2C) prevents microtubule bundling - Sanchez, C; Perez, M; Avila, J; (European Journal Of Cell Biology, 2000)

Initial studies with high resolution TEM and electron energy loss spectroscopy studies of ferritin cores extracted from brains of patients with progressive supranuclear palsy and Alzheimer disease. - Quintana C., Lancin M., Marhic C., Pérez M., Martin-Benito J., Avila J., Carrascosa J. (Cellular And Molecular Biology, 2000)

The expression of casein kinase 2a and phosphatase 2A activity - Pérez M, Avila J (Biochimica Et Biophysica Acta-Molecular Cell Research, 1999)

Polymerization of tau peptides into fibrillar structures. The effect of FTDP-17 mutations - Arrasate M, Pérez M, Armas-Portela R, Avila J (Febs Letters, 1999)

The tau gene A0 allele and progressive supranuclear palsy - Hoenicka J, Pérez M, Pérez-Tur J, Barabash A, Godoy M, Vidal L, Astarloa R, Avila J, Nygaard T, de Yébenes JG (Neurology, 1999)

Ferritin is associated with the aberrant tau filaments present in progressive supranuclear palsy - Montejo de Garcini Guedas, Esteban; Perez Martinez, Maria Mar; Perez, M; Valpuesta, JM; de Garcini, EM; Quintana, C; Arrasate, M; Lopez-Carrascosa, JL; Rabano, A; de Yebenes, JG; Avila, J (American Journal Of Pathology, 1998)

Tau glycation is involved in aggregation of the protein but not in the formation of filaments - Ledesma, MD; Pérez, M; Colaco, C; Avila, J; (Cellular And Molecular Biology, 1998)

Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment - Pérez M, Wandosell F, Colaço C, Avila J (Biochemical Journal, 1998)

Role of glycosaminoglycans in determining the helicity of paired helical filaments - Arrasate M, Pérez M, Valpuesta JM, Avila J (American Journal Of Pathology, 1997)

Isolation and characterization of a rabbit epididymal secretory glycoprotein that associates to the spermatozoon surface - Nieto, A; Sagal, RG; Martinez, MP (Molecular Reproduction And Development, 1997)

A putative B-tubulin phosphate-binding motif is involved in lateral microtubule protofilament interactions - Perez, M; Aloria, K; Zabala, JC; Avila, J; (European Journal Of Biochemistry, 1997)

Interactions of progesterone-dependent endometrial nuclear factors with the promoter of the rabbit uteroglobin gene - Pérez Martínez M, García C, López de Haro MS, Nieto A (Archives Of Biochemistry And Biophysics, 1996)

Protein kinases involved in the phosphorylation of human tau protein in transfected COS-1 cells - Medina M, García-Rocha M, Padilla R, Pérez M, Montejo de Garcini E, Avila J (Biochimica Et Biophysica Acta. Molecular Basis Of Disease, 1996)

Polymerization of ? into filaments in the presence of heparin: The minimal sequence required for ?-? interaction - Montejo de Garcini Guedas, Esteban; Perez Martinez, Maria Mar (Journal Of Neurochemistry, 1996)

Binding of Apolipoprotein E3 to tau protein: Effects on tan glycation, tau phosphorylation and tau microtubule binding in vitro - Ledesma MD; Moreno FJ; Perez MM; Avila J (Alzheimer's Research, 1996)

Glycogen synthase kinase 3 phosphorylates recombinant human tau protein at serine-262 in the presence of heparin (or tubulin) - Moreno FJ; Medina M; Pérez M; Montejo de Garcini E; Avila J (Febs Letters, 1995)

Isolation and characterization of two isoforms of a retinoic acid-binding protein from rabbit epididymal secretions - Regalado F, Pérez Martínez M, López de Haro MS, Nieto A (Biochimica Et Biophysica Acta-General Subjects, 1994)

Binding of retinoids to uteroglobin - López de Haro MS, Pérez Martínez M, García C, Nieto A (Febs Letters, 1994)

Purified uteroglobin lacks anti-proteinase activity - López de Haro MS, Pérez Martínez M, Nieto A (Biochemistry International, 1992)

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction - Pérez M, Valpuesta JM, Medina M, Montejo de Garcini E, Avila J (Journal Of Neurochemistry, 1996)

Efecto de tau en la respuesta inflamatoria de la microglía - Perez Martinez, Maria Mar (Autor o Coautor); Ávila de Grado, Jesús (Director) (2020)

Phosphorylation, microtubule binding and aggregation of tau protein in Alzheimer's disease - Perez Martinez, Maria Mar (Alzheimer´s Disease: Advances In Etiology, Pathogenesis And Therapeutics, 2001)

Aprendizaje Basado en Equipos Conducido por Proyectos. Aprendizaje de contenidos a través de la adquisición de competencias no específicas de materia - Pérez Martínez, María del Mar; Arredondo Lamas, Juan J (Cuadernos De Pedagogía, 2023)