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Author profile at the institutional portal

Cuadrado Pastor, Antonio antonio.cuadrado@uam.es

Bioquímica / Universidad Autónoma de Madrid

Publications

Transcription Factor NRF2 Participates in Cell Cycle Progression at the Level of G1/S and Mitotic Checkpoints

  • Lastra, Diego
  • Escoll, Maribel
  • Cuadrado, Antonio;

Antioxidants - 1/5/2022

10.3390/antiox11050946 View at source

  • ISSN 20763921

Altered Blood and Brain Expression of Inflammation and Redox Genes in Alzheimer's Disease, Common to APP(V717I) x TAU(P301L) Mice and Patients

  • Cucos, Catalina Anca
  • Milanesi, Elena
  • Dobre, Maria
  • Musat, Ioana Andreea
  • Manda, Gina
  • Cuadrado, Antonio;

International Journal Of Molecular Sciences - 1/5/2022

10.3390/ijms23105799 View at source

  • ISSN 14220067

Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson’s Disease

  • Duarte P
  • Michalska P
  • Crisman E
  • Cuadrado A
  • León R

Antioxidants - 1/2/2022

10.3390/antiox11020247 View at source

  • ISSN 20763921

Overlooked and valuable facts to know in the NRF2/KEAP1 field

  • Kopacz A
  • Rojo AI
  • Patibandla C
  • Lastra-Martínez D
  • Piechota-Polanczyk A
  • Kloska D
  • Jozkowicz A
  • Sutherland C
  • Cuadrado A
  • Grochot-Przeczek A
... View more Collapse

Free Radical Biology And Medicine (p. 37-49) - 1/11/2022

10.1016/j.freeradbiomed.2022.08.044 View at source

  • ISSN 08915849

The current status and future prospects for therapeutic targeting of KEAP1-NRF2 and β-TrCP-NRF2 interactions in cancer chemoresistance

  • Srivastava R, Fernández-Ginés R, Encinar JA, Cuadrado A, Wells G

Free Radical Biology And Medicine (p. 246-260) - 1/11/2022

10.1016/j.freeradbiomed.2022.09.023

  • ISSN 08915849
  • iMarina

Dipeptide Repeat Pathology in C9orf72-ALS Is Associated with Redox, Mitochondrial and NRF2 Pathway Imbalance

  • Jimenez-Villegas, Jose
  • Kirby, Janine
  • Mata, Ana
  • Cadenas, Susana
  • Turner, Martin R.
  • Malaspina, Andrea
  • Shaw, Pamela J.
  • Cuadrado, Antonio
  • Rojo, Ana, I;
... View more Collapse

Antioxidants - 1/10/2022

10.3390/antiox11101897 View at source

  • ISSN 20763921

Brain-Protective Mechanisms of Transcription Factor NRF2: Toward a Common Strategy for Neurodegenerative Diseases

  • Cuadrado A

Annual Review Of Pharmacology And Toxicology (p. 255-277) - 6/1/2022

10.1146/annurev-pharmtox-052220-103416

  • ISSN 03621642
  • iMarina

Reduced Blood RGS2 Expression in Mild Cognitive Impairment Patients

  • Milanesi E
  • Cucos CA
  • Matias-Guiu JA
  • Piñol-Ripoll G
  • Manda G
  • Dobre M
  • Cuadrado A
... View more Collapse

Frontiers In Aging Neuroscience - 29/9/2021

10.3389/fnagi.2021.738244 View at source

  • ISSN 16634365

NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS

  • Jimenez-Villegas, J.
  • Ferraiuolo, L.
  • Mead, R. J.
  • Shaw, P. J.
  • Cuadrado, A.
  • Rojo, A. I.;

Free Radical Biology And Medicine (p. 125-141) - 1/9/2021

10.1016/j.freeradbiomed.2021.07.022 View at source

  • ISSN 08915849

α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks

  • García-Yagüe ÁJ
  • Lastres-Becker I
  • Stefanis L
  • Vassilatis DK
  • Cuadrado A

Molecular Neurobiology (p. 6697-6711) - 1/12/2021

10.1007/s12035-021-02558-9 View at source

  • ISSN 08937648

This researcher has no books.

Perspectives on the Clinical Development of NRF2-Targeting Drugs

  • Lastra D
  • Fernández-Ginés R
  • Manda G
  • Cuadrado A

Handbook Of Experimental Pharmacology (p. 93-141) - 1/1/2021

10.1007/164_2020_381 View at source

  • ISSN 01712004

Reactive Oxygen Species Network Pharmacology and Therapeutic Applications Preface

  • Schmidt, HHHW
  • Ghezzi, P
  • Cuadrado, A

Handbook Of Experimental Pharmacology (p. V-VI) - 1/1/2021

  • ISSN 01712004
  • iMarina

Regulation of phospholipids metabolism by Ras proteins

  • CARNERO, A
  • CUADRADO, A
  • DOLFI, F
  • JIMENEZ, B
  • DELPESO, L
  • ESTEVE, P
  • MONTANER, S
  • EMBADE, N
  • RAMOS, A
  • LACAL, JC;
... View more Collapse

Gtpase-Controlled Molecular Machines. Challenges In Moderm Medicine (p. 321-340) - 1/1/1994

  • iMarina

TRANSCRIPTION FACTOR NRF2 REGULATES THE PERMEABILITY OF THE BLOOD BRAIN BARRIER AT THE LEVEL OF ANGPT1/2-TIE2 SIGNALING

  • Cazalla, E
  • Garcia-Yague, AJ
  • Pajares, M
  • Jimenez-Villegas, J
  • Cuadrado, A

Free Radical Biology And Medicine (p. 16-17) - 20/5/2023

10.1016/j.freeradbiomed.2023.03.083 View at source

  • ISSN 08915849

EXPLORING THE INTERPLAY OF TRANSCRIPTION FACTOR NRF2, REDOX HOMEOSTASIS AND RNA METABOLISM IN ALS PATHOGENESIS

  • Jimenez-Villegas, J
  • Cuadrado, A
  • Rojo, AI

Free Radical Biology And Medicine (p. 7-7) - 20/5/2023

10.1016/j.freeradbiomed.2023.03.051 View at source

  • ISSN 08915849

TARGETING THE NRF2/BETATRCP AXIS IN LIVER DISEASE

  • Cuadrado, A
  • Rojo, AI
  • Fernandez-Gines, R

Free Radical Biology And Medicine (p. 10-10) - 20/8/2022

  • ISSN 08915849
  • iMarina

Targeting NRF2 for brain protection in Alzheimer's disease

  • Cuadrado, A
  • Rojo, A I
  • Manda, G

Febs Open Bio (p. 60-61) - 1/7/2021

  • ISSN 22115463
  • iMarina

An inhibitor of the NRF2-beta TrCP interaction suppresses lipopolysaccharid-mediated inflammation in vitro and in vivo

  • Fernandez-Gines, Raquel
  • Rojo, Ana I.
  • Antonio Encinar, Jose
  • Wells, Geoffrey
  • Cuadrado, Antonio;

FREE RADICAL BIOLOGY AND MEDICINE - 1/1/2021

10.1016/j.freeradbiomed.2020.12.298 View at source

  • ISSN 08915849

Regulation of the extracellular matrix glycoprotein Reelin by the transcription factor NRF2: A protective mechanism for the brain under oxidative stress

  • Garcia-Yague, Angel J.
  • Cuadrado, Antonio;

Free Radical Biology And Medicine - 1/1/2021

10.1016/j.freeradbiomed.2020.12.398 View at source

  • ISSN 08915849

Altered inflammation and redox networks in the blood of patients with mild dementia

  • Cuadrado, Antonio
  • Milanesi, Elena
  • Dobre, Maria
  • Cucos, Anca
  • Pinol-Ripoll, Gerard
  • Tudose, Catalina
  • Niculescu, Gabriela
  • Manda, Gina;
... View more Collapse

Free Radical Biology And Medicine - 1/1/2021

10.1016/j.freeradbiomed.2020.12.407 View at source

  • ISSN 08915849

WIP induces oxidant tolerance in glioblastoma cells through NRF2/KEAP1 axis regulation

  • Lastra, Diego
  • Robledinos-Anton, Natalia
  • Cuadrado, Antonio
  • Escoll, Maribel;

Free Radical Biology And Medicine - 1/1/2021

10.1016/j.freeradbiomed.2020.12.422 View at source

  • ISSN 08915849

Distinctive under-expression profile of inflammatory and redox genes in the blood of elderly patients with cardiovascular disease

  • Milanesi, Elena
  • Manda, Gina
  • Dobre, Maria
  • Codrici, Elena
  • Victoria Neagoe, Ionela
  • Ovidiu Popescu, Bogdan
  • Spiru, Luiza
  • Tudose, Catalina
  • Ioan Prada, Gabriel
  • Irene Davidescu, Eugenia
  • Pinol-Ripoll, Gerard
  • Cuadrado, Antonio;
... View more Collapse

Free Radical Biology And Medicine - 1/1/2021

10.1016/j.freeradbiomed.2020.12.348 View at source

  • ISSN 08915849

Oxidative stress and inflammation gene expression changes in cognitive impairment

  • Milanesi, E.
  • Dobre, M.
  • Popescu, B. O.
  • Prada, G.
  • Bajenaru, O.
  • Tudose, C.
  • Spiru, L.
  • Manda, G.
  • Cuadrado, A.;
... View more Collapse

Febs Open Bio (p. 229-229) - 1/1/2019

  • ISSN 22115463
  • iMarina

This researcher has no working papers.

This researcher has no technical reports.

NRF2 as a novel therapeutic target in early and intermediate age-related macular degeneration

  • Cuadrado Pastor, Antonio (Investigador principal (IP))

Period: 01-12-2022 - 30-11-2025

Type of funding: Internal

Amount of funding: 253275,00 Euros.

  • iMarina

DESARROLLO DE NUEVOS FÁRMACOS ANTI-INFLAMATORIOS BASADOS EN LA ACTIVACIÓN DEL FACTOR DE TRANSCRIPCIÓN NRF2

  • Rojo Sanchís, Ana Isabel (Investigador/a)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))

Period: 01-12-2021 - 30-11-2023

Type of funding: National

Amount of funding: 149500,00 Euros.

  • iMarina

El factor de transcripción nrf2 en la patofisiología de la enfermedad de Alzheimer

  • Pajares Cabetas, Marta (Investigador/a)
  • GARCIA YAGUE, ANGEL JUAN (Investigador/a)
  • FERNANDEZ GINES, RAQUEL (Investigador/a)
  • LASTRA MARTINEZ, DIEGO (Investigador/a)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))
  • Robledinos Anton, Natalia (Investigador/a)
  • Escoll Guerrero, Maria Isabel (Investigador/a)
  • Rojo Sanchís, Ana Isabel (Investigador principal (IP))
... View more Collapse

Period: 01-06-2020 - 31-05-2023

Type of funding: National

Amount of funding: 369050,00 Euros.

  • iMarina

Investigacion traslacional sobre la regulacion farmacologica nrf2 en enfermedades no transmisibles

  • ENCINAR HIDALGO, JOSÉ ANTONIO (Investigador/a)
  • RODRIGUEZ FRANCO, Maria Isabel (Investigador/a)
  • Fernández Fernández, Inmaculada (Investigador/a)
  • FUENTES RODRIGUEZ, JOSE MANUEL (Investigador/a)
  • MATIAS-GUIU ANTEM, JORDI (Investigador/a)
  • DUARTE PÉREZ, JOSÉ MANUEL (Investigador/a)
  • LABANDEIRA GARCIA, JOSE LUIS (Investigador/a)
  • Montaner Villalonga, Joan (Investigador/a)
  • OLIVA MIGUEL, BALDOMERO (Investigador/a)
  • FERRÁNDIZ MANGLANO, MARIA LUISA (Investigador/a)
  • Garcia Lopez, Manuela (Investigador/a)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))
... View more Collapse

Period: 01-01-2020 - 31-12-2021

Type of funding: National

Amount of funding: 20000,00 Euros.

  • iMarina

Desarrollo de fármacos activadores de NRF2 para terapias innovadoras de la enfermedad de alzheimer

  • Pajares Cabetas, Marta (Investigador/a)
  • GARCIA YAGUE, ANGEL JUAN (Investigador/a)
  • Robledinos Anton, Natalia (Investigador/a)
  • Rojo Sanchís, Ana Isabel (Investigador/a)
  • Garcia Lopez, Manuela (Investigador principal (IP))
  • MARTA PAJARES CABETAS (Miembro del equipo de investigación)
  • Angel Juan Garcia Yague (Miembro del equipo de investigación)
  • NATALIA ROBLEDINOS ANTON (Miembro del equipo de investigación)
  • MARIA ISABEL ESCOLL GUERRERO (Miembro del equipo de investigación)
  • Ana Isabel Rojo Sanchis (Miembro del equipo de investigación)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))
... View more Collapse

Period: 01-01-2018 - 31-12-2021

Amount of funding: 95091,66 Euros.

  • iMarina

Aproximación teranostica avanzada en cáncer combinando terapia fotodinámica y nano partículas

  • Cuadrado Pastor, Antonio (Investigador principal (IP))

Period: 01-05-2016 - 30-04-2019

Type of funding: National

Amount of funding: 49000,00 Euros.

  • iMarina

RED DE INVESTIGACION EN NRF2 COMO NODO DEL PATOGENOSOMA

  • Cuadrado Pastor, Antonio (Investigador principal (IP))

Period: 01-12-2015 - 30-11-2017

Type of funding: National

Amount of funding: 35000,00 Euros.

  • iMarina

PAPEL DE NRF2 COMO MODULADOR ANTIOXIDANTE DE LA NEUROINFLAMACION EN LA ENFERMEDAD DE ALZHEIMER

  • Cuadrado Pastor, Antonio (Investigador principal (IP))
  • Rada Llano, Patricia Pilar (Investigador/a)
  • Ana Isabel Rojo Sanchis (Investigador/a)
  • Lastres Becker, Isabel (Investigador/a)
  • Angel Juan Garcia Yague (Investigador/a)

Period: 01-01-2014 - 31-12-2016

  • iMarina

Papel del factor de transcripción NRF2 en diferenciación neuronal, neuroprotección y neuroinflamación.

  • Rada Llano, Patricia Pilar (Investigador/a)
  • Espada Serrano, Sandra (Investigador/a)
  • Nuria Troyano Suarez (Investigador/a)
  • Nadia Innamorato (Investigador/a)
  • Lastres Becker, Isabel (Investigador/a)
  • Angel Juan Garcia Yague (Investigador/a)
  • Ana Isabel Rojo Sanchis (Investigador/a)
  • Agnieszka Jazwa (Investigador/a)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))
... View more Collapse

Period: 01-01-2011 - 31-12-2013

  • iMarina

Regulación del factor de transcripción NRF2, organizador central de la respuesta antioxiantes célular por la vía P13K/AKT/GSK-3BETA Utilidad terpeutica en modelos animales parkinson.

  • Sagarra Conde, Maria Rosa (Investigador/a)
  • Ana Isabel Rojo Sanchis (Investigador/a)
  • Cuadrado Pastor, Antonio (Investigador principal (IP))

Period: 10-01-2007 - 10-04-2010

  • iMarina

Análisis de la función del factor de transcripción NRF2 en la progresión tumoral

  • Antonio Cuadrado (Director)
  • Escoll Guerrero, Maria Isabel (Director) Doctorando: Diego Lastra Martínez

13/1/2023

  • iMarina

Novel NRF2 inducers and selective MAO-B inhibitors for the treatment of Parkinson’s disease

  • Rafael León Martínez (Director)
  • Antonio Cuadrado (Director) Doctorando: Pablo Duarte Flórez

16/9/2022

  • iMarina

Desarrollo de nuevos moduladores de actividad del factor de transcripción NRF2

  • Antonio Cuadrado (Director)
  • Ana Isabel Rojo Sanchis (Director) Doctorando: Raquel Fernández Ginés

1/1/2022

  • iMarina

Hematopoietic Stem Cell Gene Editing for the Treatment of Pyruvate Kinase Deficiency

  • Quintana Bustamante, Oscar (Director)
  • Segovia Sanz, José C. (Director)
  • Cuadrado Pastor, Antonio (Tutor) Doctorando: Fañanás Baquero, Sara

18/9/2020

  • iMarina

The coming of age of selective types of autophagy for the treatment of Alzheimer´s disease and related tauopathies

  • Buendia Abaitua, Izaskun (Autor o Coautor)
  • Cuadrado Pastor, Antonio (Autor o Coautor)
  • Garcia Lopez, Manuela (Director)

1/1/2020

  • iMarina

Identificación de proteínas asociadas al inhibidor de la traducción elF4E-BP2 como nuevas dianas en la isquemia cerebral

  • Alcázar González, Alberto (Director)
  • Cuadrado Pastor, Antonio (Tutor) Doctorando: Martínez Alonso, Emma

14/6/2019

  • iMarina

Orchestration of the neural stem cell fate by NRF2 and TAZ

  • Portillo Perez, Francisco (Tutor)
  • Cuadrado, Antonio (Director)
  • Rojo Sanchís, Ana Isabel (Autor o Coautor)

1/1/2019

  • iMarina

Transcription factor NRF2 regulates the expression of autophagy genes

  • Antonio Cuadrado (Director)
  • Ana Isabel Rojo Sanchis (Director)
  • Rojo Sanchís, Ana Isabel (Autor o Coautor) Doctorando: Marta Pajares Cabetas

19/10/2018

  • iMarina

Papel de la oligomerización de las pl3k de clase ia p110 alfa y p110 beta en la regulación de la actividad de pten

  • Cuadrado Pastor, Antonio (Autor o Coautor)
  • Lopez Corcuera, Beatriz (Autor o Coautor)
  • Carrera Ramírez, Ana Clara (Director)
  • Lopez Corcuera, Beatriz (Tutor)

1/1/2014

  • iMarina

Protection against paracetamol-induced adverse effects in the liver by the inhibition of the protein tyrosine phosphatase 1B

  • Cuadrado Pastor, Antonio (Autor o Coautor)
  • Martínez Valverde, Angela María (Director)

1/1/2013

  • iMarina

Treatment of NRF2-related diseases

  • Cuadrado Pastor, Antonio (Autor o Coautor)
  • FERNANDEZ GINES, RAQUEL (Autor o Coautor)
  • Leon Martinez, Rafael (Autor o Coautor)
  • FRANCO GONZALEZ, JUAN FELIPE (Autor o Coautor)
  • Garcia Lopez, Manuela (Autor o Coautor)
  • Rojo Sanchís, Ana Isabel (Autor o Coautor)

21/7/2022

  • iMarina

Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-BETA-TRCP interaction for use in the treatment of fatty liver disease

  • Rojo Sanchís, Ana Isabel (Autor o Coautor)
  • RODRIGUEZ FRANCO, Maria Isabel (Autor o Coautor)
  • Garcia Lopez, Manuela (Autor o Coautor)
  • FRANCO GONZALEZ, JUAN FELIPE (Autor o Coautor)
  • FERNANDEZ GINES, RAQUEL (Autor o Coautor)
  • Leon Martinez, Rafael (Autor o Coautor)
  • ENCINAR, JOSÉ ANTONIO (Autor o Coautor)
  • Cuadrado Pastor, Antonio (Autor o Coautor)
... View more Collapse

13/1/2022

  • iMarina

Compuestos inductores de NRF2 e inhibidores de MAO-b para el tratamiento de la enfermedad de parkinson

  • Cuadrado Pastor, Antonio (Autor o Coautor)

1/1/2022

  • iMarina
Last data update: 4/24/24 1:01 PM